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13113-08-1

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13113-08-1 Usage

Uses

N-(3-Indolylacetyl)glycine,is an amino acid conjugates of indole-3-acetic acid (IAA), which has shown similar binding behavior to immobilized human serum albumin,and thus can be used as tumor therapeutic.It is also a phytotoxic conjugates of Indole-3-acetic Acid, which are shown to be the potential agents for biochemical selection of plant mutants in conjugate hydrolysis.

Check Digit Verification of cas no

The CAS Registry Mumber 13113-08-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,1 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13113-08:
(7*1)+(6*3)+(5*1)+(4*1)+(3*3)+(2*0)+(1*8)=51
51 % 10 = 1
So 13113-08-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H12N2O3/c15-11(14-7-12(16)17)5-8-6-13-10-4-2-1-3-9(8)10/h1-4,6,13H,5,7H2,(H,14,15)(H,16,17)

13113-08-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[[2-(1H-indol-3-yl)acetyl]amino]acetic acid

1.2 Other means of identification

Product number -
Other names N-indol-3-ylacetyl-glycine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13113-08-1 SDS

13113-08-1Synthetic route

methyl [(1H-indol-3-ylacetyl)amino]acetate
25365-79-1

methyl [(1H-indol-3-ylacetyl)amino]acetate

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; for 1.5h;99%
1-(1H-benzotriazol-1-yl)-2-(1H-indol-3-yl)ethanone
1080025-88-2

1-(1H-benzotriazol-1-yl)-2-(1H-indol-3-yl)ethanone

glycine
56-40-6

glycine

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
Stage #1: 1-(1H-benzotriazol-1-yl)-2-(1H-indol-3-yl)ethanone; glycine With triethylamine In water; acetonitrile at 20℃; for 1h;
Stage #2: With hydrogenchloride In water; acetonitrile
40%
indolyl acetyl chloride
50720-05-3

indolyl acetyl chloride

glycine
56-40-6

glycine

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
With sodium hydroxide; diethyl ether
indole-3-acetic acid
87-51-4

indole-3-acetic acid

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

triethylamine
121-44-8

triethylamine

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
With tetrahydrofuran anschliessendes Behandeln mit Glycin in wss. NaOH;
1H-indol-3-acetohydrazide
5448-47-5

1H-indol-3-acetohydrazide

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
With hydrogenchloride; diethyl ether; sodium nitrite Behandeln des Reaktionsprodukts mit Glycin, wss. NaOH und wss. Na2CO3;
Indole-3-acetic acid methyl ester
1912-33-0

Indole-3-acetic acid methyl ester

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ethanol; N2H4+H2O
2: diethyl ether; aqueous HCl; NaNO2 / Behandeln des Reaktionsprodukts mit Glycin, wss. NaOH und wss. Na2CO3
View Scheme
indole-3-acetic acid
87-51-4

indole-3-acetic acid

2-(2-(1H-indol-3-yl)acetamido)acetic acid
13113-08-1

2-(2-(1H-indol-3-yl)acetamido)acetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol / dichloromethane / 0 - 20 °C
2: sodium hydroxide / methanol / 1.5 h / 20 °C
View Scheme

13113-08-1Downstream Products

13113-08-1Relevant articles and documents

Preparation of synthetic auxin-amino acid conjugates

Revelou, Panagiota-Kyriaki,Constantinou-Kokotou, Violetta

, p. 1708 - 1712 (2019)

Auxin amide conjugates are regulators of the most important auxin, indole-3-acetic acid (IAA), which is considered responsible for many important processes within the plants. Herein, amide conjugates of IAA were synthesized employing a simple and efficient coupling method with WSCI·HCl, a water-soluble condensing reagent, in the presence of 1-hydroxybenzotriazole. IAA conjugates with 10 amino acids along with their corresponding methyl esters were prepared in excellent yields, up to 95%, aiming to facilitate their identification in plant species. Eight IAA-amino acid methyl ester conjugates are characterized here for the first time.

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