131150-38-4Relevant academic research and scientific papers
Synthesis of a new C2-symmetric molecule with dimeric hydroxyethylene isosteric moiety
Chakraborty,Dutta
, p. 4163 - 4172 (2007/10/03)
As part of our studies directed toward the development of new HIV protease inhibitors, a new type of C2-symmetric molecule having a dimeric hydroxyethylene isosteric moiety is synthesised by Cu(II)-mediated dimerisation of the sodium enolate of
NON-RACEMIZING SYNTHESIS AND STEREOSELECTIVE REDUCTION OF CHIRAL α-AMINO KETONES
Reetz, M. T.,Drewes, M. W.,Lennick, K.,Schmitz, A.,Holdgruen, X.
, p. 375 - 378 (2007/10/02)
α-Amino acids can be doubly benzylated at nitrogen, forming N,N-dibenzyl amino acids which can be converted into α-amino ketones 4 without appreciable racemization.The latter undergo stereoselective reduction with NaBH4 under non-chelation control to form
