13117-94-7

Basic information

• Product Name: 6-TERT-BUTYL-O-TOLUIDINE
• Synonyms: 6-TERT-BUTYL-2-METHYLANILINE;6-TERT-BUTYL-O-TOLUIDINE;2-tert-Butyl-6-methylaniline;Aniline, 2-tert-butyl-6-methyl-;Benzenamine, 2-(1,1-dimethylethyl)-6-methyl-;Butylotoluidine;6-tert-butyl-o-toluidine96+%;6-tert-Butyl-o-toluidine (NH2=1)
• CAS NO: 13117-94-7
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.26
• EINECS: 236-044-4
• Mol File: 13117-94-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 250°C
• Flash Point: 103.1 °C
• Appearance: /
• Density: 0,96 g/cm3
• Refractive Index: 1.5400 to 1.5440
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 6-TERT-BUTYL-O-TOLUIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-TERT-BUTYL-O-TOLUIDINE(13117-94-7)
• EPA Substance Registry System: 6-TERT-BUTYL-O-TOLUIDINE(13117-94-7)

Safety Data

• Statements: 23/24/25
• Safety Statements: 26-36/37/39-45
• RIDADR: 2810
• Hazardous Substances Data: 13117-94-7(Hazardous Substances Data)

Usage

General Description

6-Tert-butyl-O-toluidine is a chemical compound that is commonly used as an intermediate in the production of dyes, pharmaceuticals, and other organic chemicals. It is a tertiary amine derivative of O-toluidine, with a tert-butyl group attached to the nitrogen atom. This chemical is known to be a skin irritant and may cause allergic skin reactions in some individuals. It is also a suspected human carcinogen, with potential adverse effects on the liver and kidneys. 6-Tert-butyl-O-toluidine is often used in industrial processes and must be handled with caution to avoid potential health risks.

Upstream product

• 78-83-1 2-methyl-propan-1-ol 
• 95-53-4 o-toluidine 
• 115-11-7 isobutene 
• 2219-82-1 2-tert-Butyl-6-methylphenol 

Downstream Products

• 41378-30-7 1-(2-methylphenyl)pyrrolidine 
• 95-53-4 o-toluidine 
• 115-11-7 isobutene 
• 91210-05-8 2-(2-tert-Butyl-6-methyl-phenylamino)-9,10-dimethoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one 
• 1602747-39-6 N-(2-tert-butyl-6-methylphenyl)-2-(2-phenyl-1H-benzo[d]imidazol-1-yl)acetamide 
• 1602747-23-8 N-(2-tert-butyl-6-methylphenyl)-2-(2-(2,5-dichlorophenyl)-1H-benzo[d]imidazol-1-yl)acetamide 
• 13117-95-8 N-(2-(tert-butyl)-6-methylphenyl)benzamide 
• 150079-35-9 formic acid-(2-tert-butyl-6-methyl-anilide) 
• 13680-30-3 1-(tert-butyl)-2-isocyanato-3-methylbenzene 

Relevant articles and documents

Highly selective amination of o-and p-alkyl phenols over Pd/Al 2O3-BaO

A series of Pd-based catalysts were prepared and examined for the amination of 2,6-dimethylphenol in a fixedbed reactor. The best results were obtained for Pd/Al2O3-BaO with a conversion of 99.89% and a selectivity of 91.16%. These catalysts were characterized using BET, XRD, XPS, TEM and NH3-TPD. Doped BaO not only improved the dispersion of the Pd particles but also decreased the acidity of the catalyst, which remarkably enhanced the selectivity and stability of the catalyst. The generality of Pd/Al 2O3-BaO for this kind of reaction was demonstrated by catalytic aminations of o- and p-alkyl phenols.

Chemical process for forming 2,6-dimethylaniline

Hydroxy aromatics are aminated to form the corresponding aromatic amine by reaction at 200°-400°C with ammonia in the presence of a cyclohexanone and water in contact with a hydrogen transfer catalyst. For example, 2,6-dimethylphenol reacts with ammonia in the presence of cyclohexanone, water and a supported palladium catalyst to form 2,6-dimethylaniline.