2219-82-1Relevant articles and documents
Deoxyalkylation of guaiacol using haggite structured V4O6(OH)4
Yan, Fei,Wen, Zhe,Wu, Kai,Cui, Kai,Mai, Fuhang,Ma, Zewei,Sang, Yushuai,Bai, Yunfei,Chen, Hong,Li, Yongdan
, p. 1922 - 1932 (2019)
When V2O5 is used for the deoxygenation of guaiacol in methanol, it is reduced in situ to haggite structured V4O6(OH)4. Guaiacol prevents further reduction of the haggite phase in methanol and haggite catalyzes the partial deoxygenation of guaiacol. Haggite is a metastable redox catalyst for the deoxygenation of guaiacol, which follows the reverse Mars-van Krevelen mechanism. In addition, haggite is also a Lewis acid catalyst and catalyzes the alkylation of guaiacol with methanol as the alkylation reagent. The main products of the guaiacol deoxyalkylation are 2,6-dimethylphenol, 2-methoxy-6-methylphenol, 2,4,6-trimethylphenol, 2,3,6-trimethylphenol, 2,3,5,6-tetramethylphenol and 6-methyl-2-tert-butylphenol. Oligomerization takes place during the reaction but it is reversible. When the reaction is performed at 300 °C for 6 h, the 83.5% total selectivity for alkylphenols is achieved with a 99.0% conversion.
Phenol o-position alkylation method
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Paragraph 0061; 0062; 0063; 0064, (2017/08/27)
The invention provides a phenol o-position alkylation method which comprises the following step: in the presence of a catalyst, a phenol substance and an alkylating agent react, wherein the catalyst is an aryl zinc salt generated from a reaction of zinc and a phenol compound; the alkylating agent is olefin; the phenol substance comprises polyphenol such as catechol and hydroquinone, and further comprises one to two alkyl groups, or halide based phenols; the alkyl group is straight-chain or branched paraffin with 1-10 carbons. By adopting the phenol o-position alkylation method, the preparation efficiency is greatly improved, and the conversion rate can be further increased. The invention further provides a method for preparing 2,6-di-tert-butyl-4-methylphenol, and a reaction kettle for preparation.
Ruthenium-catalyzed rearrangement of cis-1-ethynyl-2-vinyloxiranes to substituted phenols
Maddirala, Shambabu Joseph,Odedra, Arjan,Taduri, Bhanu Pratap,Liu, Rai-Shung
, p. 1173 - 1176 (2007/10/03)
Catalytic cyclization of cis-1-ethynyl-2-vinyloxiranes was implemented with TpRuPPh3(CH3CN)2PF6 catalyst (10 mol%), to give 2,6-disubstituted phenols in reasonable yields. Under similar conditions, 1,1,2,2-tetrasubstituted oxirane gave the 2,3,6-trisubstituted phenol with skeleton reorganization. On the basis of 2H- and l3C-labeling results, we propose that the reaction mechanism involves electrocyclization of ruthenium-vinylidene intermediate with cleavage of the carbon-oxygen bond of the epoxide. Georg Thieme Verlag Stuttgart.
