1311981-49-3Relevant academic research and scientific papers
Synthesis of histidinoalanine: A comparison of β-lactone and sulfamidate electrophiles
Taylor, Carol M.,De Silva, Samanthi Thabrew
, p. 5703 - 5708 (2011/09/16)
Previous syntheses of histidinoalanine (HAL) have led to mixtures of regioisomers and/or stereoisomers. For example, opening of N-Cbz-d-serine- β-lactone (6) with Boc-l-His-OMe (5) gave a 2:1 mixture of τ- and π-regioisomers. The sulfamidate 10, derived f
