1311989-67-9Relevant academic research and scientific papers
Design, synthesis and cytotoxic activities of novel hybrid compounds between dihydrobenzofuran and imidazole
Chen, Wen,Yang, Xiao-Dong,Li, Yan,Yang, Li-Juan,Wang, Xue-Quan,Zhang, Gao-Lan,Zhang, Hong-Bin
, p. 4250 - 4255 (2011/07/29)
A series of novel hybrid compounds between dihydrobenzofuran and imidazole has been prepared and evaluated in vitro against a panel of human tumor cell lines. The results suggest that substitution of the imidazolyl-1-position with an electron-donating dihydrobenzofuran, and the imidazolyl-3-position with a naphthylacyl or electron-rich phenacyl group, were vital for modulating cytotoxic activity.
