131205-61-3

Upstream product

• 109-65-9 1-bromo-butane 
• 2321-07-5 fluorescein 
• 518-47-8 fluorescein disodium salt 
• 518-45-6 fluorescein free acid 

Downstream Products

• 335193-91-4 3'-O-butylfluorescein 
• 676362-51-9 6'-O-(N-maleimido-D-3,3-diphenylalanyl)-3'-O-butylfluorescein 

Relevant academic research and scientific papers

Aggregation-induced emission and solid fluorescence of fluorescein derivatives

We report herein for the first time that the aggregation-induced emission and strong solid fluorescence of fluorescein derivatives can be realized by slightly modifying their structure, which provides a new option for AIEgens and solid fluorescent materia

Optically-Detectable Enzyme Substrates and Their Method of Use

The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay.

General strategy for the preparation of membrane permeable fluorogenic peptide ester conjugates for in vivo studies of ester prodrug stability

To study ester prodrug stability properties in living cells we have conjugated fluorogenic esters to the cell membrane permeable peptide Arg 9. The desired conjugates are prepared by coupling N-maleoyl amino acid esters of monoalkylated fluoresceins or fluorescein to TyrArg 9Cys. The photophysical properties of the monoalkylated fluorescein derivatives are described.

Fluorescein-fullerene dyads: A new kind of fullerene dyad - Synthesis and their photophysical properties

Two novel fluorescein-C60 dyads have been synthesized. Fluorescence quenching in the dyads indicates a photoinduced intramolecular electron transfer from the fluorescein to the C60 moiety. (C) 2000 Elsevier Science Ltd.