131229-61-3

Basic information

• Product Name: [butoxy-(4-methylbenzoyl)amino] acetate
• Synonyms: [butoxy-(4-methylbenzoyl)amino] acetate
• CAS NO: 131229-61-3
• Molecular Formula: C₁₄H₁₉NO₄
• Molecular Weight: 265.31
• Mol File: 131229-61-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 350.5°Cat760mmHg
• Flash Point: 165.8°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 4.38E-05mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: [butoxy-(4-methylbenzoyl)amino] acetate(CAS DataBase Reference)
• NIST Chemistry Reference: [butoxy-(4-methylbenzoyl)amino] acetate(131229-61-3)
• EPA Substance Registry System: [butoxy-(4-methylbenzoyl)amino] acetate(131229-61-3)

Safety Data

• Hazardous Substances Data: 131229-61-3(Hazardous Substances Data)

Usage

General Description

[Butoxy-(4-methylbenzoyl)amino] acetate is a chemical compound with the molecular formula C14H19NO4. [butoxy-(4-methylbenzoyl)amino] acetate is an ester, containing an acetate group and a substituted benzoyl group attached to an amino group. It is commonly used as a UV filter in sunscreen and skincare products due to its ability to absorb and dissipate ultraviolet radiation. Additionally, it is also used as a stabilizer and preservative in various cosmetic and personal care products. However, it is important to note that some studies have raised concerns about the potential harmful effects of this chemical on human health and the environment, so its use is a subject of ongoing research and scrutiny.

InChI:InChI=1/C14H19NO4/c1-4-5-10-18-15(19-12(3)16)14(17)13-8-6-11(2)7-9-13/h6-9H,4-5,10H2,1-3H3

Upstream product

• 28100-85-8 4-methylbenzhydroxamic acid potassium salt 
• 106269-33-4 butyl p-methylbenzohydroxamate 
• 94-08-6 4-methylbenzoic acid ethyl ester 
• 563-63-3 silver(I) acetate 
• 139259-78-2 butyl N-chloro-p-methylbenzohydroxamate 

Downstream Products

• 19277-56-6 n-butyl 4-methylbenzoate 
• 64-19-7 acetic acid 
• 5579-27-1 1,4-dimethyl-1,4-diphenyl-2-tetrazine 

Relevant articles and documents

Evidence for the Formation of Nitrenium Ions in the Acid-catalysed Solvolysis of Mutagenic N-Acetoxy-N-Alkoxybenzamides

In aqueous acetonitrile, N-acetoxy-N-alkoxybenzamides undergo acid-catalysed solvolysis by the AAl1 mechanism to give acetic acid and nitrenium ions.This is indicated by an inverse dependence of the acid-independent rate constant, kH, upon the activity of water, a solvent kinetic isotope effect of 0.44 and positive Σ(excit.) values.In addition, relief of steric compression at the nitrogen enhances the rate of solvolysis.Hammett correlations with ?+ substituent constants were found for the rates of solvolysis of para-substituted-N-acetoxy-N-butoxybenzamides and N-acetoxy-N-(para-substituted benzyloxy) benzamides.This fact and the low ρ-values of -1.35 and -1.56, respectively, are indicative of a strong build-up of positive charge in the transition state which has both nitrenium ion and oxonium ion character and is in accordance with computed molecular-orbital properties of N-alkoxynitrenium ions.Greater levels of mutagenicity have been measured for those compounds which are more readily solvolysed to nitrenium ions.