1312310-27-2

Basic information

• Product Name: ethyl 4-([(benzyloxy)carbonyl]amino)-2-oxo-4-phenylbutanoate
• Synonyms: ethyl 4-([(benzyloxy)carbonyl]amino)-2-oxo-4-phenylbutanoate
• CAS NO: 1312310-27-2
• Molecular Weight: 355.39
• Mol File: 1312310-27-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-([(benzyloxy)carbonyl]amino)-2-oxo-4-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-([(benzyloxy)carbonyl]amino)-2-oxo-4-phenylbutanoate(1312310-27-2)
• EPA Substance Registry System: ethyl 4-([(benzyloxy)carbonyl]amino)-2-oxo-4-phenylbutanoate(1312310-27-2)

Safety Data

• Hazardous Substances Data: 1312310-27-2(Hazardous Substances Data)

Upstream product

• 383366-27-6 benzyl phenyl(phenylsulfonyl)methylcarbamate 
• 100-52-7 benzaldehyde 
• 98253-69-1 2-(trimethylsilyloxy)acrylic acid ethyl ester 
• 136401-24-6 benzyl N-(1-methoxy-1-phenylmethyl)carbamate 
• 621-84-1 O-benzyl carbamate 

Relevant articles and documents

Catalytic syntheses of γ-functionalized α-keto esters from thioacetals and N,O-acetals

Ethyl 2-(trimethylsilyloxy)acrylic ester (1a) reacts with thioacetals providing the corresponding α-keto-γ-thio esters in good to satisfactory yields. Whereas aminals do not react, N,O-acetals lead to γ-amino-α-keto esters in good to excellent yields. All reactions proceed under mild reaction conditions, and no additional work up is required. Subsequent transformations of the obtained products to the corresponding α-oximes have been demonstrated.