1312445-63-8 Usage
Uses
Used in Oncology:
NVP-BKM120 (Hydrochloride) is used as an antineoplastic agent for its ability to inhibit the PI3K signaling pathway, which is involved in the growth and proliferation of cancer cells. This makes it a promising treatment option for various types of cancer.
Used in Brain Tumor Treatment:
Due to its good blood-brain barrier penetration, NVP-BKM120 (Hydrochloride) is used as a potential treatment for brain tumors, where the PI3K signaling pathway may also play a role in tumor growth and proliferation.
Used in Preclinical Cancer Research:
NVP-BKM120 (Hydrochloride) is used in preclinical studies to evaluate its efficacy in a variety of cancer models, providing valuable insights into its potential as a cancer therapy.
Used in Clinical Trials:
NVP-BKM120 (Hydrochloride) is currently being evaluated in clinical trials to assess its safety, tolerability, and potential effectiveness in cancer therapy, further exploring its role as a promising candidate for treating various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1312445-63-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,4,4 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1312445-63:
(9*1)+(8*3)+(7*1)+(6*2)+(5*4)+(4*4)+(3*5)+(2*6)+(1*3)=118
118 % 10 = 8
So 1312445-63-8 is a valid CAS Registry Number.
1312445-63-8Relevant academic research and scientific papers
MANUFACTURING PROCESS FOR PYRIMIDINE DERIVATIVES
-
, (2012/04/17)
The invention relates to processes for manufacturing a compound of formula (5) or a stereoisomer, tautomer or a salt thereof, wherein the substituents are as defined in the specification. The invention further relates to new manufacturing processes for specific solid forms of Compound A and its salts, to such solid forms and to use of said solid forms for the therapeutic treatment of warm-blooded animals.
