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944401-56-3

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944401-56-3 Usage

General Description

2-Amino-5-bromo-4-trifluoromethylpyridine is a chemical compound with the formula C6H4BrF3N2. It is a pyridine derivative with a bromine substituent at the 5-position and a trifluoromethyl group at the 4-position. 2-AMINO-5-BROMO-4-TRIFLUOROMETHYLPYRIDINE is widely used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active molecules, such as pharmaceutical drugs and crop protection chemicals. It is also used as a reagent in organic synthesis to introduce the amino and bromo functional groups into organic molecules. 2-Amino-5-bromo-4-trifluoromethylpyridine is known for its high reactivity and ability to participate in a wide range of chemical reactions, making it a valuable tool in synthetic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 944401-56-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,4,0 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 944401-56:
(8*9)+(7*4)+(6*4)+(5*4)+(4*0)+(3*1)+(2*5)+(1*6)=163
163 % 10 = 3
So 944401-56-3 is a valid CAS Registry Number.
InChI:InChI:1S/C6H10BrF3N2/c7-4-2-12-5(11)1-3(4)6(8,9)10/h3-5,12H,1-2,11H2

944401-56-3 Well-known Company Product Price

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  • Alfa Aesar

  • (H64936)  2-Amino-5-bromo-4-(trifluoromethyl)pyridine, 95%   

  • 944401-56-3

  • 250mg

  • 542.0CNY

  • Detail
  • Alfa Aesar

  • (H64936)  2-Amino-5-bromo-4-(trifluoromethyl)pyridine, 95%   

  • 944401-56-3

  • 1g

  • 1813.0CNY

  • Detail
  • Aldrich

  • (730483)  2-Amino-5-bromo-4-(trifluoromethyl)pyridine  95%

  • 944401-56-3

  • 730483-500MG

  • 1,421.55CNY

  • Detail

944401-56-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-4-(trifluoromethyl)pyridin-2-amine

1.2 Other means of identification

Product number -
Other names 5-bromo-4-(trifluoromethyl)pyridin-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:944401-56-3 SDS

944401-56-3Relevant articles and documents

Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo[2,1-f][1,2,4]triazine derivatives

Chen, Yan-Hong,Ding, Jian,Meng, Ling-Hua,Wang, Yi,Xiang, Hao-Yue,Yang, Chun-Hao,Zhang, Xi

, (2020)

A series of 6-aminocarbonyl pyrrolo[2,1-f][1,2,4]triazine derivatives were designed by scaffold hopping strategy. The IC50 values of compound 14a against PI3Ks were measured, showing selective activity against p110α and p110δ with IC50s of 122 nM and 119 nM respectively. All the synthesized compounds were evaluated for their antiproliferative activity against human cancer cells by SRB assay. Compounds 14a, 14p and 14q exhibited potent antiproliferative activity against five types of human cancer cells and the PK property of 14q was also investigated here.

Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors

-

Paragraph 0302-0306; 0381-0383, (2018/03/01)

The present invention relates to compounds of general formula I, wherein the groups R1, R2 and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.

4-(AZETIDIN-1-YL)PYRIMIDINE DERIVATIVES WITH ANTI-MITOTIC AND ANTI-PROLIFERATIVE ACTIVITY

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Paragraph 0161; 0162, (2017/11/04)

The invention relates to 4-(azetidin-1-yl)pyrimidyl compounds of formula (I), wherein X and Y are, independently of each other CH or N; U is O, CHOH, CHCH2OH, C(CH3)OH, CO, CHNH2; R1 and R2 are, independently of each other H, F or CH3; and R3 is H or CH3; and related compounds with anti-mitotic and anti-proliferative properties, and methods of making use of such compounds in therapy or diagnostics to attenuate undesired cell proliferation, growth, migration, metastasis tumor formation, and inflammatory conditions. Additionally, methods are disclosed of treating diseases associated with undesired angiogenesis and undesired proliferation, and methods of treating infectious and inflammatory diseases using such compounds.

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