1312450-64-8Relevant academic research and scientific papers
Palladium-catalyzed synthesis of 2-cyanoindoles from 2-gem-dihalovinylanilines
Zeidan, Nicolas,Bognar, Sabine,Lee, Sophia,Lautens, Mark
supporting information, p. 5058 - 5061 (2017/11/07)
An efficient Pd(0)-catalyzed synthesis of 2-cyanoindoles from 2-gem-dihalovinylanilines is reported. Few methods have aimed to synthesize these scaffolds which are found in many natural products and have high bioactivity. This protocol features a robust c
Rapid, robust, clean, catalyst-free synthesis of 2-halo-3-carboxyindoles
Kunzer, Aaron R.,Wendt, Michael D.
supporting information; experimental part, p. 1815 - 1818 (2011/05/05)
A novel synthesis of 2-halo-3-carboxyindoles from 2-(2,2-dihalovinyl) anilines was discovered. Reaction conditions and substrate applicability were studied. Optimally, the reaction takes only minutes when these substrates are heated in DMSO at 120 °C in t
