1312537-05-5

Basic information

• Product Name: 5-bromo-N-(2,2,2-trifluoroethyl)-N'-[4-(trifluoromethyl)-pyrimidin-2-yl]benzene-1,3-diamine
• Synonyms: 5-bromo-N-(2,2,2-trifluoroethyl)-N'-[4-(trifluoromethyl)-pyrimidin-2-yl]benzene-1,3-diamine
• CAS NO: 1312537-05-5
• Molecular Weight: 415.136
• Mol File: 1312537-05-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-N-(2,2,2-trifluoroethyl)-N'-[4-(trifluoromethyl)-pyrimidin-2-yl]benzene-1,3-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-N-(2,2,2-trifluoroethyl)-N'-[4-(trifluoromethyl)-pyrimidin-2-yl]benzene-1,3-diamine(1312537-05-5)
• EPA Substance Registry System: 5-bromo-N-(2,2,2-trifluoroethyl)-N'-[4-(trifluoromethyl)-pyrimidin-2-yl]benzene-1,3-diamine(1312537-05-5)

Safety Data

• Hazardous Substances Data: 1312537-05-5(Hazardous Substances Data)

Upstream product

• 33786-90-2 5‐bromobenzene‐1,3‐diamine 
• 1312537-04-4 5-bromo-N-(2,2,2-trifluoroethyl)benzene-1,3-diamine 
• 33034-67-2 2-chloro-4-trifluoromethylpyrimidine 
• 18242-39-2 3,5-dinitrobromobenzene 

Downstream Products

• 1312537-06-6 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2,2,2-trifluoroethyl)-N-4-[(trifluoromethyl)pyrimidin-2-yl]benzene-1,3-diamine 
• 1312505-44-4 1-[5-(3-[(2,2,2-trifiuoroethyl)amino]-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]cyclobutanol 

Relevant articles and documents

AMINOPYRIMIDINES AS SYK INHIBITORS

The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.