13127-79-2Relevant articles and documents
Synthesis and crystal structure of N,N-BIS[(4-aminophenoxy)ethyl]benzene sulfonamide
Jiang, Guang-Qi,Lu, Yong-Zhong,Cai, Jie
, p. 2854 - 2856 (2014/06/09)
The reaction of diethanol amine and benzene sulfonyl chloride produced the benzene sulfonate intermediates, then it was nucleophilicly substituted by 4-nitrophenol and subsequently reduced by hydrazine hydrate in the presence of activated carbon and iron(
PROCESS FOR PREPARATION OF SUBSTANTIALLY OPTICALLY PURE LEVOROTATORY AND DEXTROROTATORY ENANTIOMERS OF CETIRIZINE USING NOVEL INTERMEDIATES
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Page/Page column 5-6, (2009/01/24)
The present invention relates to a novel and commercially viable process for substantially optically pure levorotatory and dextrorotatory enantiomers of cetirizine intermediate, 1-[(4-chlorophenyl)phenylmethyl]piperazine, thereby producing substantially optically pure levorotatory and dextrorotatory enantiomers of cetirizine and their pharmaceutical acceptable acid addition salts thereof in high purity and in high yield using novel intermediates.