131270-16-1

Basic information

• Product Name: (R)-3-N,N-dibenzylamino-4-phenylbutanoic acid
• Synonyms: (R)-3-N,N-dibenzylamino-4-phenylbutanoic acid
• CAS NO: 131270-16-1
• Molecular Weight: 359.468
• Mol File: 131270-16-1.mol

Chemical Properties

• CAS DataBase Reference: (R)-3-N,N-dibenzylamino-4-phenylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-N,N-dibenzylamino-4-phenylbutanoic acid(131270-16-1)
• EPA Substance Registry System: (R)-3-N,N-dibenzylamino-4-phenylbutanoic acid(131270-16-1)

Safety Data

• Hazardous Substances Data: 131270-16-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 137428-37-6 (S)-3-N,N-dibenzylamino-4-hydroxybutanenitrile 
• 131270-09-2 (S)-2-N,N-dibenzylamino-3-cyanopropanoic acid benzyl ester 
• 137428-34-3 (S)-(-)-N,N-dibenzylasparagine benzyl ester 
• 131270-10-5 (S)-3-N,N-dibenzylamino-4-mesyloxybutanenitrile 
• 128916-04-1 (S)-N,N-dibenzylasparagine 
• 131270-13-8 (R)-3-N,N-dibenzylamino-4-phenylbutanenitrile 

Downstream Products

• 131270-08-1 (R)-3-amino-4-phenylbutanoic acid 

Relevant articles and documents

General synthesis of enantiomerically pure β-amino acids

An efficient method for the synthesis of chiral β-amino acids starting from (S)-asparagine is shown. The key intermediate is an activated β-homoserine equivalent, which can be reacted with organocuprates to yield β-N,N-dibenzylamino nitrite derivatives. After deprotection the β-amino acids are obtained enantiomerically pure in high overall yield.