1312719-50-8Relevant articles and documents
Synthesis, molecular modelling and biological activity of some pyridazinone derivatives as selective human monoamine oxidase-B inhibitors
?zdemir, Zeynep,Alag?z, Mehmet Abdullah,Uslu, Harun,Karakurt, Arzu,Erikci, Acelya,Ucar, Gulberk,Uysal, Mehtap
, p. 692 - 704 (2020/03/11)
Background: Since brain neurotransmitter levels are associated with the pathology of various neurodegenerative diseases like Parkinson and Alzheimer, monoamineoxidase (MAO) plays a critical role in balancing these neurotransmitters in the brain. MAO isofo
The novel synthesized pyridazinone derivates had the antiproliferative and apoptotic effects in SHSY5Y and HEP3B cancer cell line
?iftci, Osman,?zdemir, Zeynep,Acar, Ceren,S?zen, Mert,Ba?ak-Türkmen, Ne?e,Ayhan, ?dris,G?zükara, Harika
, p. 323 - 331 (2018/04/20)
Background: Brain cancer (neuroblastoma) and liver cancer (hepatocellular carcinoma) are common cancer types among others worldwide which do not have a radical treatment and cure. Objective: In the current study, five novel pyridazinone derivates bearing
Synthesis and in vitro antimycobacterial activities of novel 6-substituted-3(2H)-pyridazinone-2-acetyl-2-(substituted/nonsubstituted acetophenone) hydrazone
Utku, Semra,Goekce, Mehtap,Aslan, Goenuel,Bayram, Guel,Uelger, Mahmut,Emekdas, Guerol,Sahin, M. Fethi
scheme or table, p. 331 - 339 (2011/12/16)
The difficulty in managing tuberculosis includes the prolonged duration of the treatment, the emergence of drug resistance, and coinfection with HIV/AIDS. Tuberculosis control requires new drugs that act on novel drug targets to help in combating resistan