1312764-25-2

Upstream product

• 6342-56-9 Pyruvic aldehyde dimethyl acetal 
• 501-53-1 benzyl chloroformate 
• 165807-05-6 4-(dimethoxymethyl)pyrimidin-2-amine 

Downstream Products

• 1312764-26-3 benzyl (4-formylpyrimidin-2-yl)carbamate 
• 1312764-27-4 1-[2-N-(benzyloxycarbonylamino)pyrimidin-4-yl]-2,2,2-trifluoroethanol 
• 1443227-32-4 benzyl (4-(1,2,4-triazin-3-yl)pyrimidin-2-yl)carbamate 
• 1443227-28-8 benzyl (4-(4,9-dihydro-3H-pyrido[3,4-b]indol-1-yl)pyrimidin-2-yl)carbamate 
• 1443227-29-9 2-(((benzyloxy)carbonyl)amino)pyrimidine-4-carboxylic acid 
• 1443227-30-2 methyl 2-(((benzyloxy)carbonyl)amino)pyrimidine-4-carboxylate 
• 1443227-31-3 benzyl (4-(hydrazinecarbonyl)pyrimidin-2-yl)carbamate 
• 1443227-33-5 benzyl (4-(9H-pyrido[3,4-b]indol-1-yl)pyrimidin-2-yl)carbamate 

Relevant academic research and scientific papers

COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES

The present invention relates to new compounds that are useful in the prevention or treatment of respiratory diseases, such as asthma, to the preparation of the compounds, and to compositions including the compounds. The present invention also relates to the use of the compounds, as well as compositions including the compounds, in treating or preventing respiratory diseases.

Two new approaches towards the synthesis of annomontine using Pictet-Spengler and aza-Diels-Alder reactions

Two new routes were established for the synthesis of biologically active natural product annomontine utilizing Pictet-Spengler and aza-Diels-Alder reactions as key steps.

AMINO-HETEROARYL DERIVATIVES AS HCN BLOCKERS

The invention relates to amino-heteroaryl derivatives having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.