131288-30-7

Basic information

• Product Name: (2R,4R)-3-Benzyloxycarbonyl-2-phenyl-4-phenylmethyl-5-oxooxazolidine
• Synonyms: (2R,4R)-3-Benzyloxycarbonyl-2-phenyl-4-phenylmethyl-5-oxooxazolidine
• CAS NO: 131288-30-7
• Molecular Weight: 387.435
• Mol File: 131288-30-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2R,4R)-3-Benzyloxycarbonyl-2-phenyl-4-phenylmethyl-5-oxooxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-3-Benzyloxycarbonyl-2-phenyl-4-phenylmethyl-5-oxooxazolidine(131288-30-7)
• EPA Substance Registry System: (2R,4R)-3-Benzyloxycarbonyl-2-phenyl-4-phenylmethyl-5-oxooxazolidine(131288-30-7)

Safety Data

• Hazardous Substances Data: 131288-30-7(Hazardous Substances Data)

Upstream product

• 2448-45-5 Cbz-D-Phe 
• 100-52-7 benzaldehyde 
• 501-53-1 benzyl chloroformate 
• 673-06-3 D-(R)-phenylalanine 

Downstream Products

• 97206-21-8 N-(benzyloxycarbonyl)-α-methyl-D-phenylalanine 
• 23239-35-2 (S)-2-amino-2-methyl-3-phenylpropanoic acid 
• 145440-43-3 (2R,4S)-4-Benzhydryloxycarbonylmethyl-4-benzyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 
• 95260-65-4 (2R,4R)-4-Benzyl-4-methyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 
• 221685-05-8 (2R,4S)-4-Benzyl-4-(benzyloxycarbamoyl-methyl)-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 
• 221685-11-6 (R)-2-Acetylamino-4-methyl-pentanoic acid ((S)-3-benzyl-1-benzyloxy-2,5-dioxo-pyrrolidin-3-yl)-amide 
• 221685-08-1 (S)-2-Acetylamino-4-methyl-pentanoic acid ((S)-3-benzyl-1-benzyloxy-2,5-dioxo-pyrrolidin-3-yl)-amide 
• 221685-06-9 ((S)-3-Benzyl-1-benzyloxy-2,5-dioxo-pyrrolidin-3-yl)-carbamic acid benzyl ester 
• 221685-12-7 (R)-2-Acetylamino-4-methyl-pentanoic acid ((S)-3-benzyl-1-hydroxy-2,5-dioxo-pyrrolidin-3-yl)-amide 
• 221685-09-2 (S)-2-Acetylamino-4-methyl-pentanoic acid ((S)-3-benzyl-1-hydroxy-2,5-dioxo-pyrrolidin-3-yl)-amide 
• 221685-07-0 (S)-3-Amino-3-benzyl-1-benzyloxy-pyrrolidine-2,5-dione 
• 145440-44-4 (2R,4S)-4-Benzyl-4-carboxymethyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 

Relevant articles and documents

Leucine-phenylalanine dipeptide-based N-mesyloxysuccinimides: Synthesis of all four stereoisomers and their assay against serine proteases

The four stereoisomers of 3-(N-acetylleucylamino)-3-benzyl-1- [(methylsulfonyl)oxy]succinimide have been prepared and shown to inhibit α- chymotrypsin and human neutrophil elastase. The structural and stereochemical features that affect the potency and selectivity of inhibition are discussed.

HETEROCYCLIC PEPTIDE RENIN INHIBITORS

A renin inhibiting compound of the formula STR1 wherein X is N, O or CH; R 1 is absent or a functional group; A and L are independently selected from absent, C=O, SO 2 and CH 2 ; D is C=O, SO. sub.2 or CH 2 ; Y is N or CH; R 2 is hydrogen, loweralkyl or substituted alkyl; Z is a functional group; R 3 is loweralkyl or substituted alkyl; n is 0 or 1; and T is a mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof.