1312952-25-2

Basic information

• Product Name: (2R)-3-(4-(benzyloxy)phenyl)-2-(5-((4-butylphenyl)ethynyl)thiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)propanamide
• Synonyms: (2R)-3-(4-(benzyloxy)phenyl)-2-(5-((4-butylphenyl)ethynyl)thiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)propanamide
• CAS NO: 1312952-25-2
• Molecular Weight: 672.866
• Mol File: 1312952-25-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-3-(4-(benzyloxy)phenyl)-2-(5-((4-butylphenyl)ethynyl)thiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-3-(4-(benzyloxy)phenyl)-2-(5-((4-butylphenyl)ethynyl)thiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)propanamide(1312952-25-2)
• EPA Substance Registry System: (2R)-3-(4-(benzyloxy)phenyl)-2-(5-((4-butylphenyl)ethynyl)thiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)propanamide(1312952-25-2)

Safety Data

• Hazardous Substances Data: 1312952-25-2(Hazardous Substances Data)

Upstream product

• 65733-15-5 (R)-2-amino-3-(4-(benzyloxy)phenyl)propanoic acid 
• 1312952-24-1 (2R)-3-(4-(benzyloxy)phenyl)-2-(5-bromothiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)propanamide 
• 79887-09-5 (4-butylphenyl)acetylene 
• 1312952-23-0 (R)-3-(4-(benzyloxy)phenyl)-2-(5-bromothiophene-2-sulfonamido)propanoic acid 
• 6723-30-4 O-2-tetrahydro-2H-pyranhydroxylamine 

Downstream Products

• 1312952-16-1 (2R)-3-(4-(benzyloxy)phenyl)-2-(5-((4-butylphenyl)ethynyl)thiophene-2-sulfonamido)-N-hydroxypropanamide 

Relevant articles and documents

Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors

Matrix metalloproteinases (MMPs) are important factors in gliomas since these enzymes facilitate invasion into the surrounding brain and participate in neovascularization. In particular, the gelatinases (MMP-2 and MMP-9), and more recently MMP-25, have be