65733-15-5Relevant academic research and scientific papers
Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases
Kristensen, Jan B.L.,Nielsen, Anders L.,Jorgensen, Lars,Kristensen, Line H.,Helgstrand, Charlotte,Juknaite, Lina,Kristensen, Jesper L.,Kastrup, Jette S.,Clausen, Rasmus P.,Olsen, Lars,Gajhede, Michael
scheme or table, p. 1951 - 1956 (2012/06/15)
To investigate ligand selectivity between the oncogenic KDM4C and tumor repressor protein KDM6A histone demethylases, KDM4C and KDM6A were enzymatically characterized, and subsequently, four compounds were tested for inhibitory effects. 2,4-dicarboxypyrid
NOVEL ANTIDIABETIC COMPOUNDS
-
Page/Page column 70-71, (2010/11/29)
The present invention provides novel compounds of the general formula (I), wherein the symbols are same as described in specification, their pharmaceutically acceptable salts, their tautomeric forms, their stereoisomers, pharmaceutical compositions containing them, to process and intermediates for the preparation of the above said compounds, having the utility of these compounds in medicine and to methods for their therapeutic use, and their use in the treatment of diabetes and related diseases.
PROCESS FOR PREPARING 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES WITHOUT RESOLUTION
-
Page/Page column 19, (2010/02/11)
The present invention discloses an improve process for the preparation of S (-) and R (+) 3-aryl-2-hydroxy propanoic acid derivatives without any resolution involved.
PROCESS FOR PRODUCING AMINOEPOXIDE
-
Page 7-8, (2010/02/10)
The present invention relates to a method of producing N-carbamate protected-3-amino-1,2-epoxy-4-(hydroxy substituted phenyl)butane at a high optical purity in a high yield, by hydrogenating N-carbamate protected-3-amino-1-chloro-2-hydroxy-4-(benzyloxy su
