1313051-55-6

Basic information

• Product Name: (R)-2-(2-methylphenyl)propan-1-ol
• Synonyms: (R)-2-(2-methylphenyl)propan-1-ol
• CAS NO: 1313051-55-6
• Molecular Weight: 150.221
• Mol File: 1313051-55-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-2-(2-methylphenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(2-methylphenyl)propan-1-ol(1313051-55-6)
• EPA Substance Registry System: (R)-2-(2-methylphenyl)propan-1-ol(1313051-55-6)

Safety Data

• Hazardous Substances Data: 1313051-55-6(Hazardous Substances Data)

Upstream product

• 552333-33-2 7-bromo-1H-isochromene-1,3(4H)-dione 
• 103108-03-8 2-(2-methylphenyl)propanal 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 201230-82-2 carbon monoxide 
• 611-15-4 1-methyl-2-vinyl-benzene 
• 62835-97-6 β,2-dimethylbenzeneethanol 
• 7572-79-4 2-(2-methylphenyl)propan-2-ol 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 7399-49-7 1-methyl-2-(prop-1-en-2-yl)benzene 
• 1313051-31-8 C₁₂H₁₆O₂ 
• 118-90-1 ortho-methylbenzoic acid 

Relevant articles and documents

Easily accessible TADDOL-derived bisphosphonite ligands: Synthesis and application in the asymmetric hydroformylation of vinylarenes

The synthesis of chiral bidentate bisphosphonite ligands based on the TADDOL motif from readily available starting materials has been developed. Taking advantage of the modular nature of the building blocks, a diverse ligand library has been prepared. Their catalytic potential has been evaluated in the asymmetric hydroformylation of styrene and derivatives. These catalysts showed high activity and provided the aldehydes in high enantiomeric purity.

Enantioselective Synthesis of 4-Methyl-3,4-dihydroisocoumarin via Asymmetric Hydroformylation of Styrene Derivatives

Enantioenriched aldehydes are produced through asymmetric hydroformylation of styrene derivatives using BIBOP-type ligands. The featured example is enantioselective synthesis of 4-methyl-3,4-dihydroisocoumarin, which was prepared in a 95.1:4.9 enantiomeric ratio from asymmetric hydroformylation of ethyl 2-vinylbenzoate followed by in situ lactonization during the reduction process. The conditions are compatible with both electron-rich and electron-poor substituents.