62835-97-6

Basic information

• Product Name: Benzeneethanol, -ba-,2-dimethyl- (9CI)
• Synonyms: Benzeneethanol,-bta-,2-dimethyl-(9CI);Benzeneethanol, -ba-,2-dimethyl- (9CI)
• CAS NO: 62835-97-6
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.21756
• Product Categories: PHENYL
• Mol File: 62835-97-6.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneethanol, -ba-,2-dimethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, -ba-,2-dimethyl- (9CI)(62835-97-6)
• EPA Substance Registry System: Benzeneethanol, -ba-,2-dimethyl- (9CI)(62835-97-6)

Safety Data

• Hazardous Substances Data: 62835-97-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 19819-98-8 2-o-tolylethanol 
• 103108-03-8 2-(2-methylphenyl)propanal 
• 1256965-79-3 1-(1-methoxyprop-1-en-2-yl)-2-methylbenzene 
• 7399-49-7 1-methyl-2-(prop-1-en-2-yl)benzene 
• 7572-79-4 2-(2-methylphenyl)propan-2-ol 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 118-90-1 ortho-methylbenzoic acid 
• 1262985-46-5 4,4,5,5-tetramethyl-2-(2-o-tolylpropyl)-1,3,2-dioxaborolane 
• 644-36-0 o-methylphenylacetic acid 
• 108-88-3 toluene 
• 75-56-9 methyloxirane 
• 137144-15-1 (rac)-2-(2-methylphenyl)propanoic acid 

Downstream Products

• 1313051-29-4 C₁₂H₁₆O₂ 
• 1313051-31-8 C₁₂H₁₆O₂ 
• 1313051-55-6 (R)-2-(2-methylphenyl)propan-1-ol 
• 180624-82-2 1-[2-(2-Methoxy-ethoxymethoxy)-1-methyl-ethyl]-2-methyl-benzene 
• 137144-17-3 1-Methoxy-2-(2-tolyl)propan 

Relevant articles and documents

Highly efficient NHC-iridium-catalyzed β-methylation of alcohols with methanol at low catalyst loadings

The methylation of alcohols is of great importance since a broad number of bioactive and pharmaceutical alcohols contain methyl groups. Here, a highly efficient β-methylation of primary and secondary alcohols with methanol has been achieved by using bis-N-heterocyclic carbene iridium (bis-NHC-Ir) complexes. Broad substrate scope and up to quantitative yields were achieved at low catalyst loadings with only hydrogen and water as by-products. The protocol was readily extended to the β-alkylation of alcohols with several primary alcohols. Control experiments, along with DFT calculations and crystallographic studies, revealed that the ligand effect is critical to their excellent catalytic performance, shedding light on more challenging Guerbet reactions with simple alcohols. [Figure not available: see fulltext.].

Iron-Catalyzed β-Alkylation of Alcohols

β-Branched alkylated alcohols have been prepared in good yields using a double-hydrogen autotransfer strategy in the presence of our diaminocyclopentadienone iron tricarbonyl complex Fe1. The alkylation of some 2-arylethanol derivatives was successfully addressed with benzylic alcohols and methanol as alkylating reagents under mild conditions. Deuterium labeling experiments suggested that both alcohols (2-arylethanol and either methanol or benzyl alcohol) served as hydrogen donors in this cascade process.

Highly Enantioselective Catalytic Kinetic Resolution of α-Branched Aldehydes through Formal Cycloaddition with Homophthalic Anhydrides

A new catalytic methodology was developed to promote an efficient one-pot kinetic resolution of racemic aldehydes with selectivity (s*) of up to 91 (99:1 d.r., >99 % ee) in a cycloaddition reaction with enolizable anhydrides to afford dihydroisocoumarin products (a core prevalent in natural products and molecules of medicinal interest) containing three contiguous stereocentres.