13132-25-7

Basic information

• Product Name: 4-TRIMETHYLSILYLPHENOL
• Synonyms: 4-TRIMETHYLSILYLPHENOL;Phenol,4-(trimethylsilyl)-
• CAS NO: 13132-25-7
• Molecular Formula: C₉H₁₄OSi
• Molecular Weight: 166.29506
• Mol File: 13132-25-7.mol
• Article Data: 17

Chemical Properties

• Melting Point: 74 °C
• Boiling Point: 230.7 °C at 760 mmHg
• Flash Point: 93.3 °C
• Appearance: /
• Density: 0.96 g/cm³
• Vapor Pressure: 0.0429mmHg at 25°C
• Refractive Index: 1.503
• PKA: 9.51±0.13(Predicted)
• CAS DataBase Reference: 4-TRIMETHYLSILYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TRIMETHYLSILYLPHENOL(13132-25-7)
• EPA Substance Registry System: 4-TRIMETHYLSILYLPHENOL(13132-25-7)

Safety Data

• Hazardous Substances Data: 13132-25-7(Hazardous Substances Data)

Usage

Definition

ChEBI: An organosilicon compound that is phenol substituted by a trimethylsilyl group at position 4.

InChI:InChI=1/C9H14OSi/c1-11(2,3)9-6-4-8(10)5-7-9/h4-7,10H,1-3H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 106-41-2 4-bromo-phenol 
• 877-68-9 4-trimethylsilylanisole 
• 855-31-2 1-(4-methoxyphenyl)-2,5-diphenyl-1H-pyrrole 
• 853-38-3 1-(4-hydroxyphenyl)-2,5-diphenyl-1H-pyrrole 
• 104-94-9 4-methoxy-aniline 
• 123-30-8 4-amino-phenol 
• 143106-12-1 tert-butyldimethyl(4-trimethylsilylphenoxy)silane 
• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 17865-11-1 (4-(trimethylsilyl)phenyl)boronic acid 
• 106-48-9 4-chloro-phenol 
• 17005-59-3 4-chlorophenoxytrimethylsilane 
• 17878-44-3 (4-bromophenoxy)trimethylsilane 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 

Downstream Products

• 17961-97-6 phosphoric acid dimethyl ester-(4-trimethylsilanyl-phenyl ester) 
• 18772-62-8 1,3-Bis-(4-trimethylsilyl-phenoxy)-propanol-⁽²⁾ 
• 17887-64-8 2-hydroxy-5-trimethylsilanyl-benzaldehyde 
• 73355-31-4 Dimethyl-[2-(4-trimethylsilanyl-phenoxy)-ethyl]-amine 
• 18001-11-1 p-(Trimethylsilyl)phenyl Acetate 
• 7450-05-7 cis-4-(trimethylsilyl)cyclohexanol 
• 18848-95-8 phosphoric acid tris-(4-trimethylsilanyl-phenyl ester) 
• 7452-94-0 (trans)-4-(trimethylsilyl)cyclohexanol 
• 1418117-88-0 4-(trimethylsilyl)phenyl pivalate 
• 1379761-65-5 4-(trimethylsilyl)phenyl mesylate 
• 1379761-52-0 C₂₂H₂₂O₄S 
• 1379761-42-8 C₂₅H₂₃NO₆S 
• 1259290-88-4 C₁₂H₁₈OSi 

Relevant articles and documents

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Palladium-catalyzed silylation of aryl chlorides with hexamethyldisilane

A method for the palladium-catalyzed silylation of aryl chlorides has been developed. The method affords desired product in good yield, is tolerant of a variety of functional groups, and provides access to a wide variety of aryltrimethylsilanes from commercially available aryl chlorides. Additionally, a one-pot procedure that converts aryl chlorides into aryl iodides has been developed.

Generation of Aryllithium Reagents from N -Arylpyrroles Using Lithium

Treatment of 1-aryl-2,5-diphenylpyrroles with lithium powder in tetrahydrofuran at 0 °C results in the generation of the corresponding aryllithium reagents through reductive C-N bond cleavage.

Method for preparing alcohol and phenol through aerobic hydroxylation reaction of boric acid derivative in absence of photocatalyst

The invention discloses a method for preparing alcohol and phenol through aerobic hydroxylation reaction of a boric acid derivative in the absence of a photocatalyst, wherein the boric acid derivativeis aryl boronic acid or alkyl boronic acid, and the corresponding target compounds are respectively a phenol-based compound and an alcohol-based compound. According to the method, by using a boric acid derivative as a reaction substrate, an additive is added under a solvent condition, and a hydroxylation reaction is performed under aerobic and illumination conditions to obtain a corresponding target compound. According to the invention, the new strategy is provided for the synthesis of phenols through aerobic hydroxylation of aryl boronic acid without a photocatalyst; the catalyst-free aerobic hydroxylation method for photocatalysis of aryl boronic acid or alkyl boronic acid by using triethylamine as an additive is firstly disclosed; and the new method has advantages of photocatalyst-freecondition, wide substrate range and good functional group compatibility.

Photoinduced hydroxylation of arylboronic acids with molecular oxygen under photocatalyst-free conditions

Photoinduced hydroxylation of boronic acids with molecular oxygen under photocatalyst-free conditions is reported, providing a green entry to a variety of phenols and aliphatic alcohols in a highly concise fashion. This new protocol features photocatalyst-free conditions, wide substrate scope and excellent functional group compatibility.