1313512-92-3

Basic information

• Product Name: (2-chloro-4-methoxy-5-((3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyloxy)triisopropylsilane
• Synonyms: (2-chloro-4-methoxy-5-((3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyloxy)triisopropylsilane
• CAS NO: 1313512-92-3
• Molecular Weight: 851.596
• Mol File: 1313512-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-chloro-4-methoxy-5-((3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyloxy)triisopropylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloro-4-methoxy-5-((3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyloxy)triisopropylsilane(1313512-92-3)
• EPA Substance Registry System: (2-chloro-4-methoxy-5-((3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyloxy)triisopropylsilane(1313512-92-3)

Safety Data

• Hazardous Substances Data: 1313512-92-3(Hazardous Substances Data)

Upstream product

• 3336-16-1 2-chloro-4-hydroxybenzonitrile 
• 1259020-48-8 5-bromo-2-chloro-4-methoxybenzoic acid 
• 1259020-79-5 5-bromo-2-chloro-4-methoxybenzonitrile 
• 1259020-46-6 5-bromo-2-chloro-4-hydroxybenzonitrile 
• 13154-24-0 triisopropylsilyl chloride 
• 1033723-31-7 (5-bromo-2-chloro-4-methoxyphenyl)methanol 
• 13096-62-3 (3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one 
• 1259020-50-2 (5-bromo-2-chloro-4-methoxybenzyloxy)triisopropylsilane 

Downstream Products

• 1313512-91-2 (2-chloro-4-methoxy-5-((3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)methanol 
• 1313512-93-4 2-(2-chloro-4-methoxy-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)phenyl)acetonitrile 
• 1313512-94-5 C₄₂H₄₂BrClO₆ 
• 1259020-54-6 2-(2-chloro-4-methoxy-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)phenyl)acetic acid 
• 1313512-98-9 2-(2-chloro-4-methoxy-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)phenyl)-N-(2-(furan-2-yl)-2-oxoethyl)acetamide 
• 1313512-99-0 2-(2-chloro-4-methoxy-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)benzyl)-5-(furan-2-yl)thiazole 
• 1313513-00-6 (2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-2-yl)thiazol-2-yl)methyl)-2-methoxyphenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol 
• 1313513-01-7 (2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(furan-3-yl)thiazol-2-yl)methyl)-2-methoxyphenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol 
• 1313513-02-8 (2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(thiophen-2-yl)thiazol-2-yl)methyl)-2-methoxyphenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol 
• 1313513-03-9 (2S,3R,4R,5S,6R)-2-(4-chloro-2-methoxy-5-((5-(thiophen-3-yl)thiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol 
• 1313513-04-0 (2S,3R,4R,5S,6R)-2-(4-chloro-2-methoxy-5-((5-phenylthiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 1313513-05-1 (2S,3R,4R,5S,6R)-2-(4-chloro-5-((5-(4-fluorophenyl)thiazol-2-yl)methyl)-2-methoxyphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 

Relevant articles and documents

Thiazolylmethyl ortho-substituted phenyl glucoside library as novel C-aryl glucoside SGLT2 inhibitors

In order to investigate SAR regarding proximal phenyl ring in novel C-aryl glucoside SGLT2 inhibitors containing a thiazole motif, a series of chemical modifications on proximal phenyl ring was conducted. During a series of lead optimization efforts, orth