1313873-24-3Relevant academic research and scientific papers
Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP)
Antoni, Frauke,Bauer, Stefanie,Bause, Manuel,Bernhardt, Günther,Buschauer, Armin,Jackson, Scott M.,K?nig, Burkhard,Locher, Kaspar P.,Manolaridis, Ioannis,Scholler, Matthias,Stark, Simone A.
, (2020)
Tariquidar derivatives have been described as potent and selective ABCG2 inhibitors. However, their susceptibility to hydrolysis limits their applicability. The current study comprises the synthesis and characterization of novel tariquidar-related inhibit
Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2)
Puentes, Cristian Ochoa,Hoecherl, Peter,Kuehnle, Matthias,Bauer, Stefanie,Buerger, Kira,Bernhardt, Guenther,Buschauer, Armin,Koenig, Burkhard
, p. 3654 - 3657 (2011/08/06)
Aiming at structural optimization of potent and selective ABCG2 inhibitors, such as UR-ME22-1, from our laboratory, an efficient solid phase synthesis was developed to get convenient access to this class of compounds. 7-Carboxyisatoic anhydride was attach
