1313883-96-3Relevant academic research and scientific papers
Synthesis and characterization of a gold(i) bis(triazolylidene) complex featuring a large [(TpMe2)2K] anion
Mendoza-Espinosa, Daniel,Priante-Flores, Armando,Rheingold, Arnold L.,Salazar-Pereda, Verónica
, p. 15533 - 15537 (2018)
In the quest of heteroleptic gold(i) complexes containing triazolylidenes (MIC) and TpMe2 ligands, we discovered that reaction of the MIC-Au-I complex 2 with potassium hydrotris-(3,5-dimethyl-1-pyrazolil) borate (KTpMe2) produces an
Readily switchable one-pot 5-exo-dig cyclization using a palladium catalyst
Mali, Jaishree K.,Takale, Balaram S.,Telvekar, Vikas N.
, p. 2231 - 2235 (2017/01/22)
A convenient, ligand-free, Pd(OAc)2-catalyzed one-pot reaction has been developed for the synthesis of oxazolines and oxazoles from easily available acid chlorides and propargylamine. The reaction pathways could be easily modulated to selectively obtain oxazolines or oxazoles by merely changing the additives. This method proceeds via in situ sequential nucleophilic addition/elimination reactions followed by an intramolecular 5-exo-dig cycloisomerization reaction. An interesting observation in this case is the effect of an additive: a basic additive such as triethylamine resulted in the formation of 5-methylene oxazolines, while an acidic additive such as acetic acid resulted in the formation of 5-methyloxazoles. With the current protocol we are able to obtain good to moderate yields of the desired product without the need for the isolation of intermediates.
Facile, selective, and regiocontrolled synthesis of oxazolines and oxazoles mediated by ZnI2 and FeCl3
Senadi, Gopal Chandru,Hu, Wan-Ping,Hsiao, Jia-Shing,Vandavasi, Jaya Kishore,Chen, Chung-Yu,Wang, Jeh-Jeng
, p. 4478 - 4481 (2012/10/30)
An expedient method for a direct approach to the selective and regiocontrolled synthesis of 2-oxazolines and 2-oxazoles mediated by ZnI 2 and FeCl3 is described. A Lewis acid promoted cyclization of acetylenic amide with various func
Tungsten and molybdenum catalyst-mediated cyclisation of N-propargyl amides
Meng, Xiangjian,Kim, Sunggak
, p. 4429 - 4431 (2011/07/29)
Tungsten and molybdenum catalysts were employed to promote the cyclisation of N-propargylic amides to afford the corresponding oxazolines or oxazines via 5-exo-dig or 6-endo-dig mode.
