131391-99-6Relevant academic research and scientific papers
Synthesis of Phenolic Coumestans via a Sequential Dehydrogenation/Oxa-Michael Addition Reaction of 2′,4′-Dihydroxyl-3-arylcoumarins
Yan, Qinfang,Jiang, Yi,Song, Xianheng,Lu, Guoqing,Zhang, Qianzhong,Du, Zhibo,Chan, Albert S. C.,Zou, Yong
, p. 5785 - 5794 (2022/04/28)
A facile and practical approach for the synthesis of natural coumestans and derivatives starting from 2′,4′-dihydroxyl-3-arylcoumarins has been developed. The process involved a seqential intramolecular dehydrogenation/oxa-Micheal reaction efficiently promoted by 1,8-diazabicyclo[5.4.0]undec-7-ene at 40 °C under metal- and ligand-free conditions with good functional group compatibility.
3-aryl coumarin derivative as well as preparation method and application thereof
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Paragraph 0102-0105, (2021/07/17)
The invention discloses a 3-aryl coumarin derivative as well as a preparation method and application thereof. The preparation method comprises the following steps of: carrying out tandem condensation-lactonization reaction on substituted phenylacetic acid
Useful Synthesis of Coumestans
Mali, R.S.,Tilve, S.G.
, p. 1781 - 1791 (2007/10/02)
A convenient synthesis of coumestans involving a combination of lithiation and Wittig reactions is described.Compounds 1a and 1b on reaction with n-butyllithium followed by treatment with diethyloxalate provide ketoesters 3a and 3b.Reaction of 3(a-b) with
