1313994-69-2

Upstream product

• 100-39-0 benzyl bromide 
• 5651-90-1 1-methyl-4-(2-propynyloxy)benzene 
• 622-79-7 benzyl azide 

Downstream Products

• 28798-81-4 (1-benzyl-[1,2,3]triazol-4-yl)methanol 

Relevant academic research and scientific papers

Lanthanum loaded CuO nanoparticles: synthesis and characterization of a recyclable catalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles and propargylamines

Lanthanum loaded CuO (LCO) nanoparticles (NPs) were successfully synthesized by a precipitation-thermal decomposition method and characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive spectra (EDS), diffuse reflectance spectra (DRS), photoluminescence (PL), X-ray photoelectron spectroscopy (XPS) and BET surface area measurements. The synthesized LCO NPs were used as a nanocatalyst for the synthesis of 1,4-disubstituted 1,2,3-triazoles by a click reaction of substituted benzyl azides and alkynes and the synthesis of propargylamines via three-component coupling reactions of aldehydes, alkynes and amines under ultrasonication. The one-pot operation, atom-economical nature, regioselectivity and good yields are the noteworthy features of this protocol. The reusability of the prepared nanocatalyst was successfully examined six times without any appreciable loss in catalytic activity.

Azide–Alkyne Cycloaddition (CuAAC) in Alkane Solvents Catalyzed by Fluorinated NHC Copper(I) Complex

A highly efficient and environmentally benign protocol for copper-catalyzed alkyne–azide cycloaddition (CuAAC) in industrially important alkane solvents was developed. New copper(I) complexes bearing NHC ligands decorated with bulky hexafluoroisopropylalk

Role of C, S, Se and P donor ligands in copper(i) mediated C-N and C-Si bond formation reactions

The first comparative study of C, S, Se and P donor ligands-supported copper(i) complexes for C-N and C-Si bond formation reactions are described. The syntheses and characterization of eight mononuclear copper(i) chalcogenone complexes, two polynuclear co

Large Cu i 8 chalcogenone cubic cages with non-interacting counter ions

Two mega size copper(i) cubic cages, [{Cu(Bptp)1.5}8(PF6-)](PF6-)7 (1) and [{Cu(Bpsp)1.5}8(PF6-)](PF6-)7 (2), supported by imidazole-2-chalcogenone ligands (Bptp = 2,6-bis(1-isopropylimidazole-2-thione)pyridine and Bpsp = 2,6-bis(1-isopropylimidazole-2-selone)pyridine) have been synthesized and characterized. The formation of ionic salts 1 and 2 was confirmed by FT-IR, multinuclear (1H, 13C, 31P and 19F) NMR, UV-vis, TGA, CHN analysis, BET analysis, single crystal X-ray diffraction and powder X-ray diffraction techniques. To the best of our knowledge, these are the first examples of a octanuclear copper(i) cluster in a perfect cubic architecture with a copper-copper distance of 8.413 ? or 8.593 ?. Interestingly, these anion-centered CuI8 cubic arrangements are not supported by cubic centered ions or face centered molecules. The formation of cationic cubic cages was accompanied by the association of twelve ligands (Bptp or Bpsp) with eight trigonal planar [CuSe3] vertices. The cationic charge of cubic cages was satisfied by eight PF6- counter anions, in which one of the PF6- anions occupies the centre of the Cu8 cube without any interaction. The copper(i) cubic cages are found to be highly active catalysts in click chemistry as well as hydroamination reactions. The scope of the catalytic reactions has been investigated with thirty-five different combinations of click reactions and six different combinations of the hydroamination of alkynes.

Ligand Synthesis Catalyst and Complex Metal Ion: Multicomponent Synthesis of 1,3-Bis(4-phenyl-[1,2,3]triazol-1-yl)-propan-2-ol Copper(I) Complex and Application in Copper-Catalyzed Alkyne-Azide Cycloaddition

A new bistriazole copper complex was synthesized by direct treatment of an alkyne, an azide, and CuI as copper salt through in situ ligand formation under a multicomponent reaction process. This complex was analyzed by XPS, TGA, DSC, and SEM techniques an

Catalytic activity of dithioic acid copper complexes in the alkyne-azide cycloaddition

Diverse dithioic acid copper complexes exhibit a high catalytic activity in the copper-catalyzed alkyne-azide cycloaddition using several solvents under different temperatures, showing a high efficiency with only 0.005 mmol catalyst/mmol alkyne or less. A dithioic acid copper complex derived from acetophenone was selected and used as the catalyst in the preparation of a library of 1,4-disubstituted-1,2,3-triazoles. This process occurred in high yields and good functional group tolerance.

Alkyne-azide cycloaddition catalyzed by Fe-Cu nanoparticles

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of catalytic amounts of Cu-Fe nanoparticles. The process represents many advantages because it does not require additional bases or reductants, and thi

The use of glucose as alternative reducing agent in copper-catalyzed alkyne-azide cycloaddition

1,2,3-triazoles were synthesized using several alkynes and azides as starting materials in the presence of glucose and catalytic amounts of Fehling reagent. This process is carried out under ambient pressure and temperature with good yields.

Effect of temperature on triazole and bistriazole formation through copper-catalyzed alkyne-azide cycloaddition

Temperature is an important factor in the copper catalyzed alkyne azide cycloaddition under oxidative conditions. 1,2,3-Triazoles were obtained in high yields when several alkynes and azides were reacted at methanol reflux using catalytic amounts of both