1314003-47-8Relevant articles and documents
PROCESS FOR THE SYNTHESIS OF PRODRUGS OF OPIOIDS
-
, (2012/07/13)
The present invention provides a process for the synthesis of opioid prodrugs. In particular, the present invention provides a process for the synthesis of opioid prodrugs comprising: treating an opioid, in the form of a salt or a freebase, with a carbonyl synthon to form an activated intermediate and subsequently reacting the activated intermediate with an amine, in the form of a salt or a freebase.