1314026-60-2Relevant academic research and scientific papers
A convenient route to functionalized 3-amino-N-methylfuro[3,2-b]pyridine-2- carboxamides
Bretéché, Anne,Marchand, Pascal,Nourrisson, Marie-Renée,Hautefaye, Patrick,De Nanteuil, Guillaume,Duflos, Muriel
, p. 4767 - 4773 (2011/07/31)
The synthesis of novel functionalized 3-amino-N-methylfuro[3,2-b]pyridine- 2-carboxamides is described from cyanopyridine intermediates. Based on the difference in halogen reactivity, ethyl [(5-bromo-2-chloropyridin-3-yl)oxy] acetate was functionalized by a palladium-catalyzed reaction, before the cyclization to the desired furo[3,2-b]pyridines.
