1314099-62-1Relevant articles and documents
Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones - A new strategy to combat malarial parasites
Mueller, Tobias,Johann, Laure,Jannack, Beate,Brueckner, Margit,Lanfranchi, Don Antoine,Bauer, Holger,Sanchez, Cecilia,Yardley, Vanessa,Deregnaucourt, Christiane,Schrevel, Joseph,Lanzer, Michael,Schirmer, R. Heiner,Davioud-Charvet, Elisabeth
, p. 11557 - 11571 (2011/09/16)
Our work on targeting redox equilibria of malarial parasites propagating in red blood cells has led to the selection of six 1,4-naphthoquinones, which are active at nanomolar concentrations against the human pathogen Plasmodium falciparum in culture and a
