131418-11-6

Basic information

• Product Name: 2-Chloro-N-methyl-isonicotinamide
• Synonyms: 2-Chloro-N-methyl-isonicotinamide;Albb-004236;2-chloro-N-methylisonicotinamide(SALTDATA: FREE);N-Methyl 2-chloroisonicotinamide
• CAS NO: 131418-11-6
• Molecular Formula: C7H7ClN2O
• Molecular Weight: 170.59628
• Product Categories: Pyridines
• Mol File: 131418-11-6.mol

Chemical Properties

• Boiling Point: 330.677°C at 760 mmHg
• Flash Point: 153.789°C
• Appearance: /
• Density: 1.264g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 2-Chloro-N-methyl-isonicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-N-methyl-isonicotinamide(131418-11-6)
• EPA Substance Registry System: 2-Chloro-N-methyl-isonicotinamide(131418-11-6)

Safety Data

• Statements: 36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 131418-11-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-N-methyl-isonicotinamide is used as an intermediate in the synthesis of various pharmaceuticals for its potential role in the development of new drugs. Its unique chemical properties and structure contribute to the creation of innovative therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Chloro-N-methyl-isonicotinamide is utilized as an intermediate in the production of crop protection products. Its chemical characteristics make it suitable for the development of effective and novel agrochemicals to enhance crop yield and protection against pests and diseases.

InChI:InChI=1/C7H7ClN2O/c1-9-7(11)5-2-3-10-6(8)4-5/h2-4H,1H3,(H,9,11)

Upstream product

• 6313-54-8 2-chloroisonicotinic acid, 
• 65287-34-5 2-chloropyridine-4-carbonyl chloride 
• 74-89-5 methylamine 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 479612-25-4 2-chloro-3,N-dimethyl-isonicotinamide 
• 329794-24-3 2,3-Dichloro-N-methyl-isonicotinamide 

Relevant articles and documents

CRBN LIGANDS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of CRBN, and the treatment of CRBN-mediated disorders.

Tyrosine kinase inhibitors

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.

Tyrosine kinase inhibitors

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.