1314357-71-5

Upstream product

• 1314357-67-9 C₂₆H₂₉BF₂O₃ 
• 100-52-7 benzaldehyde 

Downstream Products

• 1314357-89-5 (S)-3,3-difluoro-4-hydroxy-4-phenylbutan-2-one 
• 1314357-98-6 (1S,3R)-2,2-difluoro-1-phenylbutane-1,3-diol 
• 1314357-91-9 (S)-4-(tert-butyldimethylsilyloxy)-3,3-difluoro-4-phenylbutan-2-one 
• 1314357-93-1 (S,Z)-methyl 5-(tert-butyldimethylsilyloxy)-4,4-difluoro-3-methyl-5-phenylpent-2-enoate 
• 1314357-95-3 (S,Z)-methyl 4,4-difluoro-5-hydroxy-3-methyl-5-phenylpent-2-enoate 
• 1314357-97-5 (S)-5,5-difluoro-4-methyl-6-phenyl-5,6-dihydro-2H-pyran-2-one 

Relevant academic research and scientific papers

Asymmetric fluoroallylboration of aldehydes

Contrary to previous reports, the homologation of benzyloxydifluorovinyllithium with bulky chiral iodomethylboronates readily provides a series of chiral γ,γ-difluoroallylboronates. Asymmetric fluoroallylboration of aldehydes with a 2-phenylbornane-2,3-diol-derived reagent provides gem-difluorinated homoallyl alcohols in good yields and 77-95% ee. Preparation of a chiral α-pyrone in >99% ee has also been described.