1314406-46-6

Basic information

• Product Name: 1-Boc-3-bromo-6-fluoroindole
• Synonyms: 1-Boc-3-bromo-6-fluoroindole;tert-butyl 3-bromo-6-fluoro-1H-indole-1-carboxylate;3-Bromo-6-fluoro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester;3-bromo-6-fluoro-1H-Indole-1-Carbocylic acid 1,1-dimethylethyl ester
• CAS NO: 1314406-46-6
• Molecular Formula: C13H13BrFNO2
• Molecular Weight: 314.1502232
• Mol File: 1314406-46-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 371.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1-Boc-3-bromo-6-fluoroindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-3-bromo-6-fluoroindole(1314406-46-6)
• EPA Substance Registry System: 1-Boc-3-bromo-6-fluoroindole(1314406-46-6)

Safety Data

• Hazardous Substances Data: 1314406-46-6(Hazardous Substances Data)

Usage

General Description

1-Boc-3-bromo-6-fluoroindole is a chemical compound that belongs to the class of indole derivatives. It is characterized by the presence of a tert-butoxycarbonyl (Boc) protective group, a bromine atom, and a fluorine atom. 1-Boc-3-bromo-6-fluoroindole can be used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals due to its potential as a building block in the production of bioactive molecules. Its unique structure and functional groups make it an important tool for medicinal and chemical research, as well as in the development of new drug candidates.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1094754-90-1 3-bromo-6-fluoro-1H-indole 
• 399-51-9 6-fluoro-1H-indole 
• 1208459-96-4 tert-butyl 6-fluoro-1H-indole-1-carboxylate 

Relevant articles and documents

Five-membered heterocyclic oxo carboxylic acid compound and medical application thereof

The invention relates to a five-membered heterocyclic oxo carboxylic acid compound and a medical application thereof. Specifically, the invention relates to a compound, a pharmaceutical salt, a prodrug, a hydrate, a solvate or a crystal form as shown in a formula (I), and also relates to a preparation method of the compound, a pharmaceutical composition containing the compound and an application of the pharmaceutical composition as a secretion regulator of interferon type I, especially as an STING agonist in preparation of medicines for preventing and/or treating I-type interferon related diseases.

NOVEL 3-INDOL SUBSTITUTED DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE

A compound of Formula I is provided: or pharmaceutically acceptable enantiomers, salts or solvates thereof. The 5 invention further relates to the use of the compounds of Formula I as TDO2 inhibitors. The invention also relates to the use of the compounds of Formula I for the treatment and/or prevention of cancer, neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease and Huntington's disease, chronic viral infections such as HCV and HIV, depression, and obesity. The invention also 10 relates to a process for manufacturing compounds of Formula I.