1314451-06-3

Upstream product

• 24595-58-2 5-phenylpent-4-yn-1-ol 
• 5390-04-5 pent-1-yn-5-ol 
• 591-50-4 iodobenzene 
• 70214-59-4 5-phenylpent-4-ynal 
• 95-54-5 1,2-diamino-benzene 
• 131529-87-8 ethyl 5-phenyl-4-pentynoate 
• 3350-92-3 5-phenylpent-4-ynoic acid 
• 63093-41-4 ethyl 4-pentynoate 
• 6089-09-4 4-pentynoic acid 

Downstream Products

• 1314451-24-5 C₁₇H₁₃IN₂ 

Relevant academic research and scientific papers

Cyclization of alk-4-ynals with o-diaminoarenes as a selective one-pot synthesis of arylmethylidene-substituted 2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazoles and 7,8-dihydro-6H-pyrrolo[1’,2’:1,2]imidazo[4,5-b]pyridines

A one-pot synthesis of arylmethylidene-substituted 2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazoles based on the reaction of alk-4-ynals with 1,2-diaminobenzenes in DMSO at sequential catalysis with NH4Br and bases was suggested. The use in these pr

Stereoselective one-pot synthesis of (1Z)- and (1E)-1-arylmethylidene-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazoles by cyclization of alk-4-ynals with o-diaminobenzene

Cyclization of alk-4-ynals with o-diaminobenzene in DMSO under the sequential action of NH4Br and base (KOH or K2CO3) affords 1-arylmethylidene-2,3-dihydro-1H-pyrrolo[1,2-a]benzimidazoles, which are formed selectively as E- or Z-isomers depending on the base used.

An effective synthetic entry to fused benzimidazoles via iodocyclization

A protocol for the synthesis of the fused heterocyclic polycyclic compounds pyrrole[1,2-a]benzimidazoles, piperidine[1,2-a]benzimidazoles and oxa-fused benzimidazoles using iodine and silver nitrate by an exo-dig or endo-dig cyclization pathway at room te