63093-41-4

Basic information

• Product Name: ethyl pent-4-ynoate
• Synonyms: ethyl pent-4-ynoate;Ethyl 4-pentynoate;4-(Ethoxycarbonyl)-1-butyne
• CAS NO: 63093-41-4
• Molecular Formula: C₇H₁₀O₂
• Molecular Weight: 126.1531
• Mol File: 63093-41-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 162.1°Cat760mmHg
• Flash Point: 50.9°C
• Appearance: /
• Density: 0.96g/cm³
• Vapor Pressure: 2.2mmHg at 25°C
• Refractive Index: 1.432
• CAS DataBase Reference: ethyl pent-4-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl pent-4-ynoate(63093-41-4)
• EPA Substance Registry System: ethyl pent-4-ynoate(63093-41-4)

Safety Data

• Hazardous Substances Data: 63093-41-4(Hazardous Substances Data)

Usage

General Description

Ethyl pent-4-ynoate is a chemical compound with the molecular formula C7H10O2. It is also known as ethyl 4-pentyne-1-oate and is commonly used as a flavoring agent in the food and beverage industry. It is a clear, colorless liquid with a fruity, banana-like odor, and is often used in the production of artificial fruit flavors. Ethyl pent-4-ynoate is also used in the manufacturing of perfumes and fragrances due to its pleasant aroma. It is important to handle and store ethyl pent-4-ynoate carefully, as it is flammable and can cause irritation to the skin, eyes, and respiratory system if not handled properly.

InChI:InChI=1/C7H10O2/c1-3-5-6-7(8)9-4-2/h1H,4-6H2,2H3

Upstream product

• 141-78-6 ethyl acetate 
• 106-96-7 propargyl bromide 
• 17920-23-9 diethyl propargylmalonate 
• 64-17-5 ethanol 
• 5390-04-5 pent-1-yn-5-ol 
• 55183-44-3 4-pentynoic chloride 
• 6089-09-4 4-pentynoic acid 
• 491862-29-4 2-ethoxycarbonyl-2-(2-propynyl)malonic acid diethyl ester 

Downstream Products

• 5390-04-5 pent-1-yn-5-ol 
• 591-80-0 pent-4-enoic acid 
• 693825-14-8 ethyl 3-(cyclohexa-1,5-dienyl)propanoate 
• 1289154-49-9 (E)-8-(α-acetyloxy-4'-methoxybenzylidenyl)-5-oxoindolizidine 
• 1289154-41-1 N-allyl-5-(4-methoxyphenyl)-4-pentynamide 
• 1289154-45-5 N-(1-hexen-3-yl)-5-(4-methoxyphenyl)-4-pentynamide 
• 1289154-24-0 C₁₇H₁₉NO₃ 
• 1314451-24-5 C₁₇H₁₃IN₂ 
• 1314451-26-7 C₁₇H₁₁Cl₂IN₂ 
• 1314451-28-9 C₁₈H₁₅IN₂O 
• 876049-26-2 5-(4-(trifluoromethyl)phenyl)pent-4-ynoic acid 

Relevant articles and documents

DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins

The huge resources that had gone into Human Immunodeficiency virus (HIV) research led to the development of potent antivirals able to suppress viral load in the majority of treated patients, thus dramatically increasing the life expectancy of people living with HIV. However, life-long treatments could result in the emergence of drug-resistant viruses that can progressively reduce the number of therapeutic options, facilitating the progression of the disease. In this scenario, we previously demonstrated that inhibitors of the human DDX3X helicase can represent an innovative approach for the simultaneous treatment of HIV and other viral infections such as Hepatitis c virus (HCV). We reported herein 6b, a novel DDX3X inhibitor that thanks to its distinct target of action is effective against HIV-1 strains resistant to currently approved drugs. Its improved in vitro ADME properties allowed us to perform preliminary in vivo studies in mice, which highlighted optimal biocompatibility and an improved bioavailability. These results represent a significant advancement in the development of DDX3X inhibitors as a novel class of broad spectrum and safe anti-HIV-1 drugs.

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses compounds according to Formula (I): (I). Wherein R1, R2, R5 and Cy are as defined herein. The present invention relates to compounds, methods for the production of said compounds, pharmaceutical compositions comprising said compounds and methods for the prophylaxis and/or treatment of inflammatory diseases, autoimmune diseases, pain, fibrosis and/or proliferative diseases by administering said compounds.

Single-Molecule Observation of the Intermediates in a Catalytic Cycle

The development of catalysts benefits from knowledge of the intermediate steps that accelerate the transformations of substrates into products. However, key transient species are often hidden in ensemble measurements. Here, we show that a protein nanoreac