1315342-48-3Relevant academic research and scientific papers
Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design
Ilies, Monica,Di Costanzo, Luigi,Dowling, Daniel P.,Thorn, Katherine J.,Christianson, David W.
, p. 5432 - 5443 (2011)
Arginase is a binuclear manganese metalloenzyme that hydrolyzes l-arginine to form l-ornithine and urea, and aberrant arginase activity is implicated in various diseases such as erectile dysfunction, asthma, atherosclerosis, and cerebral malaria. Accordin
