1315563-69-9Relevant academic research and scientific papers
Iron-catalyzed nitrene insertion reaction for facile construction of amide compounds
Chen, Guo-Qiang,Xu, Zhen-Jiang,Liu, Yungen,Zhou, Cong-Ying,Che, Chi-Ming
, p. 1174 - 1178 (2011)
A facile method for the construction of amide compounds from aldehydes by an iron-catalyzed nitrene insertion reaction has been developed. Both aryl and aliphatic aldehydes can directly afford the corresponding amides with an iron(II)-terpyridine (tpy) complex formed in situ as catalyst, and PhI=NTs as nitrogen source under mild reaction conditions. An ESI-MS study revealed the formation of [Fe(tpy)NTs)]+ as a reaction intermediate. Georg Thieme Verlag Stuttgart - New York.
