131614-82-9

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 15384-34-6 D-lyxono-1,4-lactone 
• 100-52-7 benzaldehyde 
• 5336-08-3 D-Ribono-1,4-lactone 

Downstream Products

• 179992-61-1 (2S,4aR,7R,7aR)-7-Azido-2-phenyl-tetrahydro-furo[3,2-d][1,3]dioxin-6-one 
• 1281872-13-6 2-azido-3,5-O-benzylidene-2-deoxy-D-lyxitol 
• 1021178-12-0 C₂₅H₂₂O₅ 
• 131614-83-0 (2S,4aR,7R,7aR)-7-hydroxy-2-phenyltetrahydro-6H-furo[3,2-d][1,3]dioxin-6-one 
• 131550-08-8 9-(2,4-O(R)-benzylidene-β-D-threo-oxetanosyl)adenine 
• 131550-06-6 methyl 2,4-anhydro-(S)-3,5-benzylidene-D-lyxonate 
• 131550-07-7 (1S,3S,6R,8R)-8-Chloro-3-phenyl-2,4,7-trioxa-bicyclo[4.2.0]octane 
• 130481-72-0 (S)-3,5-O-benzylidene-2-O-trifluoromethanesulfonyl-D-xylono-1,4-lactone 
• 944329-21-9 C₁₂H₁₆N₄O₂ 
• 944329-20-8 C₂₀H₂₄N₄O₅S 

Relevant academic research and scientific papers

Enantiomeric 2-acetamido-1,4-dideoxy-1,4-iminoribitols as potential pyrrolidine hexosaminidase inhibitors

2-Acetamido-1,4-imino-1,2,4-trideoxy-D-ribitol (DRBNAc) and the enantiomeric LRBNAc were prepared as potential hexosaminidase inhibitors from L- and D-lyxonolactone, respectively. Neither N-benzyl-DRBNAc nor N-benzyl-LRBNAc showed any inhibition of α- or

Efficient synthesis from d-lyxonolactone of 2-acetamido-1,4-imino-1,2,4-trideoxy-l-arabinitol LABNAc, a potent pyrrolidine inhibitor of hexosaminidases

The synthesis from d-lyxonolactone of 2-acetamido-1,4-imino-1,2,4-trideoxy-l-arabinitol LABNAc proceeded in an overall yield of 25%; the enantiomer, 2-acetamido-1,4-imino-1,2,4-trideoxy-d-arabinitol DABNAc, was prepared from l-lyxonolactone. LABNAc and N-

Spectroscopic, crystallographic and computational studies of the formation and isomerization of cyclic acetals and ketals of pentonolactones

The different reactivities of D-ribonolactone, L-arabinonolactone, D-xylonolactone, D-lyxonolactone and 2-deoxy-D-ribonolactone toward benzaldehyde and acetone in acidic media, were examined. The reactions involved complex equilibria and were investigated with extensive 13C NMR studies as well as X-ray crystallographic analysis of selected products. Molecular mechanics (MM2) and semiempirical (PM3 and AM1) calculations of some derivatives were carried out in order to facilitate structural and conformational assignments. The differences in reactivity observed for the reactions of D-pentono-1,4-lactones with benzaldehyde and acetone are rationalized in terms of their structural and conformational features.

Synthesis from D-lyxonolactone of 1,4-dideoxy-1,4-imino-L-arabinitol, a glucosidase inhibitor with in vitro anti-viral activity

Benzylidenation is the only protection required in a 7 step synthesis of the hydrochloride of 1,4-dideoxy-1,4-imino-L-arabinitol from D-lxyonolactone in an overall yield of 21%.

Use of D-Ribonolactone in Organic Synthesis. 2. Scope and Utility

The scope and utility of D-ribonolactone (1) as chiral template for the synthesis of optically active γ-lactones which are important precursors for many natural products are discussed.The regio- and stereoselective functionalization of 1 is examined.