131666-49-4

Basic information

• Product Name: (2S,4R)-6-tert-butoxy-2,4-dihydroxy-6-oxohexyl benzoate
• Synonyms: (2S,4R)-6-tert-butoxy-2,4-dihydroxy-6-oxohexyl benzoate
• CAS NO: 131666-49-4
• Molecular Weight: 324.374
• Mol File: 131666-49-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4R)-6-tert-butoxy-2,4-dihydroxy-6-oxohexyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-6-tert-butoxy-2,4-dihydroxy-6-oxohexyl benzoate(131666-49-4)
• EPA Substance Registry System: (2S,4R)-6-tert-butoxy-2,4-dihydroxy-6-oxohexyl benzoate(131666-49-4)

Safety Data

• Hazardous Substances Data: 131666-49-4(Hazardous Substances Data)

Upstream product

• 124655-09-0 1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate 
• 98-88-4 benzoyl chloride 
• 131666-50-7 ((4S,6R)-6-(2-tert-butoxy-2-oxoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)methyl benzoate 
• 131690-27-2 (5S)-6-benzoyloxy-5-hydroxy-3-oxohexanoic acid tert-butyl ester 

Downstream Products

• 1235588-94-9 tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2-phenyl-1,3-dioxan-4-yl)acetate 
• 1235588-97-2 tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2-phenyl-1,3-dioxan-4-yl)acetate 
• 355806-00-7 rosuvastatin tert-butyl ester 

Relevant articles and documents

New Statin intermediate, the preparation of the same and the preparation of Rosuvastatin using the same

The present invention provides a novel producing method for producing a core intermediate (chemical formula IV) of rosuvastatin, a novel intermediate used therefor and a producing method of rosuvastatin hemi-calcium salts using the same. The novel intermediate of the present invention can be prepared with high purity and in high yields in mild conditions, and thus the rosuvastatin intermediate and rosuvastatin hemi-calcium salts can be conveniently and efficiently mass-produced without complicated processes.