131699-67-7 Usage
General Description
1,3-dimethyl-6-oxiranyl-2,4-pyrimidinedione, also known as etirasid, is a pharmaceutical compound with potential antitumor activity. It is a synthetic compound that inhibits various enzymatic pathways involved in cell proliferation and survival, making it a promising candidate for cancer treatment. Etirasid is known to inhibit the activity of thymidylate synthase, an enzyme essential for DNA synthesis, and has been studied for its potential use in the treatment of various types of cancer, including colorectal and lung cancer. Its unique molecular structure and mechanism of action make etirasid a valuable chemical compound for further research and development in the field of oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 131699-67-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,6,9 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 131699-67:
(8*1)+(7*3)+(6*1)+(5*6)+(4*9)+(3*9)+(2*6)+(1*7)=147
147 % 10 = 7
So 131699-67-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O3/c1-9-5(6-4-13-6)3-7(11)10(2)8(9)12/h3,6H,4H2,1-2H3
131699-67-7Relevant articles and documents
Researches on antiviral agents. 3. Synthesis and transformations of racemic and chiral 6-oxiranyl pyrimidinones
Botta, Maurizio,Saladino, Raffaele,Lamba, Doriano,Nicoletti, Rosario
, p. 6053 - 6070 (2007/10/02)
The synthesis of epoxides 3, 4 and 6 has been described. The transformation of 3 into C-6 alkylated uracils 22a-e, 23a-d, 24 and 25 is also reported. The chiral epoxide (S)-(+)-3 has been prepared via a modified Solladie procedure, while the ZnCl2- DIBAH reduction step failed to give the expected enantiomer (R)-(-)-3. This result has been discussed on the ground of molecular modeling studies.
