131747-32-5

Basic information

• Product Name: (4-nitropyridin-2-yl)methyl acetate
• Synonyms: (4-nitropyridin-2-yl)methyl acetate
• CAS NO: 131747-32-5
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.16012
• Mol File: 131747-32-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4-nitropyridin-2-yl)methyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-nitropyridin-2-yl)methyl acetate(131747-32-5)
• EPA Substance Registry System: (4-nitropyridin-2-yl)methyl acetate(131747-32-5)

Safety Data

• Hazardous Substances Data: 131747-32-5(Hazardous Substances Data)

Usage

General Description

(4-nitropyridin-2-yl)methyl acetate is a chemical compound that consists of a pyridine ring with a nitro group and a methyl acetate group attached to it. It is commonly used in organic synthesis as a building block in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. The nitro group makes it a strong electrophile, allowing it to participate in a variety of organic reactions such as nitro reduction, nucleophilic aromatic substitution, and transition metal-catalyzed coupling reactions. The presence of the methyl acetate group also gives the compound some reactivity, making it useful in the formation of carbon-carbon and carbon-nitrogen bonds. Additionally, the compound's high stability and low reactivity towards common reagents make it a valuable intermediate in the synthesis of more complex organic molecules.

Upstream product

• 5470-66-6 2-methyl-4-nitropyridine N-oxide 
• 108-24-7 acetic anhydride 
• 931-19-1 2-methylpyridine N-oxide 

Downstream Products

• 108337-77-5 2-(N-Benzyl-N-methylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(4-nitro-2-pyridyl)-3,5-pyridinedicarboxylate 
• 108338-19-8 4-nitro-2-pyridinecarboxaldehyde 

Relevant articles and documents

Chiral amine-imine ligands based on trans-2,5-disubstituted pyrrolidines and their application in the palladium-catalyzed allylic alkylation

A series of amine-imine bidentate ligands based on a trans-2,5-disubstituted pyrrolidine and pyridine moieties have been prepared. The use of these ligands in the palladium-catalyzed allylic alkylation reaction of rac-(E)-1,3-diphenylprop-2-enyl acetate is reported. The results suggest that these ligands are good catalyst precursors for the reaction. Electronic modification on the pyridine ring of the ligands does not have a significant effect on the enantioselectivity of the reaction but does on the reaction rate, while structural modification on either the pyridine or the pyrrolidine moiety affords dramatic changes on the outcome of the stereochemistry. Evidence from various studies suggested that during the palladium-catalyzed allylic alkylation reaction, nucleophilic attack onto the 1,3-diphenylallyl moiety in the transition state occurs mainly trans to the pyridine ring of the less stable conformation of the palladium complexes.

Method for labelling phosphorylated peptides, complex compounds used in the methods, process for producing the same, and their intermediates

Provided are a method for easily detecting phosphorylated peptides, namely, proteins, in samples derived from living organisms or the like, a method for selectively adsorbing the phosphorylated peptides, and compounds that are highly coordinated to the phosphorylated peptides and usable in the methods. The complex compound is represented by the formula: wherein X is a linker moiety, and Y is a labeling group. The compound (I) is highly coordinated to a phosphorylated peptide. and has a labeling group. Accordingly, with use of the compound (I), the phosphorylated peptide can be easily identified.

Novel 1,4-dihydropyridine calcium antagonists. I. Synthesis and hypotensive activity of 4-(substituted pyridyl)-1,4-dihydropyridine derivatives

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