131748-91-9

Basic information

• Product Name: 2-BROMO-5-BROMOMETHYL-THIAZOLE
• Synonyms: 2-BROMO-5-BROMOMETHYL-THIAZOLE;Thiazole, 2-broMo-5-(broMoMethyl)-;2-bromo-5-(bromomethyl)-1,3-thiazole
• CAS NO: 131748-91-9
• Molecular Formula: C₄H₃Br₂NS
• Molecular Weight: 256.95
• EINECS: 205-525-8
• Product Categories: ADVANCED CHEMICALS;Heterocycles
• Mol File: 131748-91-9.mol
• Article Data: 12

Chemical Properties

• Melting Point: 64-66°C
• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Solubility: Chloroform; Dichloromethane; DMSO; Ethyl Acetate
• CAS DataBase Reference: 2-BROMO-5-BROMOMETHYL-THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-BROMOMETHYL-THIAZOLE(131748-91-9)
• EPA Substance Registry System: 2-BROMO-5-BROMOMETHYL-THIAZOLE(131748-91-9)

Safety Data

• Hazardous Substances Data: 131748-91-9(Hazardous Substances Data)

Usage

Uses

2-Bromo-5-bromomethylthiazole is an intermediate in the synthesis of Deschloro-2-bromo-thiamethoxam (D290785), an impurity of thiamethoxam (T344180), which is a neonicotinoid insecticide. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.

Upstream product

• 41731-23-1 2-bromo-5-methyl-1,3-thiazole 
• 687636-93-7 (2-bromothiazole-5-yl)methanol 

Downstream Products

• 131748-92-0 2-bromo-5-thiazolylmethylamine 
• 1383851-36-2 N-[(2-bromo-1,3-thiazol-5-yl)methyl]-N-[3-(1H-imidazol-2-yl)-2-phenyl-1-benzofuran-6-yl]methanesulfonamide 

Relevant articles and documents

PqsR INVERSE AGONISTS

The present invention relates to a compound according to general formula (I), which acts as an inhibitor of PqsR (the currently only known receptor for the Pseudomonas Quinolone Signal (PQS)); to a pharmaceutical composition containing one or more of the compound(s) of the invention; to a combination preparation containing at least one compound of the invention and at least one further active pharmaceutical ingredient; and to uses of said compound(s), including the use as a medicament, e.g. the use in the treatment or prophylaxis of a bacterial infection, especially a Pseudomonas aeruginosa or Burkholderia infection.

Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor

Disclosed are thiazole methylamino pyridine compounds represented by the general formula (I) having fungicidal, insecticidal/acaricidal, and herbicidal activity, the preparation method thereof, the fungicidal, insecticidal/acaricidal, and herbicidal compositions containing the compounds of the present invention, and the use and the method for controlling fungi, insects/acari and weeds of the compounds of the present invention.

METHODS, COMPOUNDS, AND COMPOSITIONS FOR THE TREATMENT OF ANGIOTENSIN-RELATED DISEASES

Disclosed are small molecule non-peptidic compounds, as well as methods and compositions for the treatment of angiotensin-related diseases and disorders, including cardiovascular diseases, metabolic diseases, gastrointestinal diseases, renal diseases, inflammatory/autoimmune diseases, neurological diseases, bone marrow diseases and cancer.