131792-50-2

Upstream product

• 131792-49-9 1-<5-(benzyloxy)-4-methoxy-2-nitrobenzal>-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 621-59-0 isovanillin 
• 1195-09-1 5-methyl-2-methoxyphenol 
• 4790-01-6 2-(benzyloxy)-1-methoxy-4-methylbenzene 
• 2495-83-2 5-(benzyloxy)-4-methoxy-2-nitrotoluene 

Downstream Products

• 131792-51-3 (RS)-9-(benzyloxy)-10-methoxyaporphine hydrochloride 

Relevant academic research and scientific papers

Isomeric Monomethyl Ether Derivatives of (RS)-9,10-Dihydroxyaporphine ("Isoapomorphine") as Possible Products of Metabolism by Catechol-O-methyltransferase

The isomeric monomethyl ether derivatives of (RS)-9,10-dihydroxyaporphine ("isoapomorphine") were synthesized unequivocally as possible metabolites in catechol-O-methyltransferase (COMT) mediated O-methylation reactions.In vitro incubation studies revealed that isoapomorphine is not a substrate for the COMT using experimental conditions under which apomorphine (10,11-dihydroxyaporphine) is converted in high yield into its 10-methyl ether, apocodeine.The in vivo dopaminergic inactivity of isoapomorphine (as compared with that of apomorphine) seems to be due to factors other than metabolic inactivation by COMT.