1318129-07-5

Upstream product

• 114676-48-1 (2S,4R)-1-benzyl-4-hydroxyproline methyl ester 
• 100-39-0 benzyl bromide 
• 1318129-92-8 1-benzyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 
• 101979-12-8 2(S)-4-cis-N-benzyl-4-hydroxyproline 
• 1318129-56-4 (2S,4S)-methyl 1-benzyl-4-(phenylcarbonyloxy)pyrrolidine-2-carboxylate 

Downstream Products

• 1318129-14-4 (3R,5R)-3-azido-1-benzyl-5-fluoropiperidine 
• 1318129-17-7 (2S,4R)-2-(azidomethyl)-1-benzyl-4-fluoropyrrolidine 
• 1318129-36-0 (3R,5R)-1-benzyl-5-fluoropiperidin-3-amine 

Relevant academic research and scientific papers

TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS

The present disclosure provides certain tricyclic compounds that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers and hemoglobinopathi

Access to optically active 3-azido- and 3-aminopiperidine derivatives by enantioselective ring expansion of prolinols

The activation of N-alkyl prolinols by XtalFluor E allowed the formation of an aziridinium intermediate that can react with tetrabutylammonium azide (nBu4NN3) to produce 3-azidopiperidines and/or 2-(azidomethyl)pyrrolidines, in a rat