131829-94-2

Upstream product

• 100-52-7 benzaldehyde 
• 17876-95-8 (trimethylsilyl)phenylmethanol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 95607-40-2 Trimethyl-[phenyl-(tetrahydro-pyran-2-yloxy)-methyl]-silane 

Downstream Products

• 492-70-6 1,2-diphenyl-1,2-ethanediol 
• 492-70-6 erythro-1,2-Diphenyl-1,2-ethanediol 
• 492-70-6 trans-stilbene dihydrodiol 
• 58176-63-9 1,2-diphenyl-2-methoxyethanol 
• 947-91-1 Diphenylacetaldehyde 
• 451-40-1 phenyl benzyl ketone 
• 95607-21-9 2-(2-Methoxy-1,2-diphenyl-ethoxy)-tetrahydro-pyran 

Relevant academic research and scientific papers

ANION RADICAL-INDUCED DESILYLATION OF ORGANOSILANE. REACTIONS OF BENZYLSILANES WITH ALDEHYDES AND RELATED COMPOUNDS IN THE PRESENCE OF BUTYLLITHIUM OR LITHIUM METAL

By the action of butyllithium or lithium metal in such polar aprotic solvent as DMF or HMPA in the presence of aldehydes or related compounds, some benzylsilanes suffer from anion radicalinduced desilylation forming benzyl carbanions which add to the aldehydes and related compounds.

A NEW METHOD FOR NUCLEOPHILIC OXYMETHYLATION USING α-ALKOXYSILANES. SYNTHESIS OF UNSYMMETRICAL 1,2-DIOLS

Desilylation of α-alkoxysilanes offers the convenient generation of carbinyl carbanions which react with a variety of carbonyl compounds giving mono-protected 1,2-diols of unsymmetrical type.Dehydration of these unsymmetrical diols leads to the regioselective formation of methyl ketones.