131933-44-3

Upstream product

• 15981-92-7 2,3'-anhydrothymidine 
• 23974-72-3 sodium phenylselenide 
• 111647-36-0 5'-O-(4,4'-dimethoxytrityl)-3'-mesyl-2',3'-dideoxythymidine 
• 191474-13-2 5'-O-(4,4'-dimethoxytrityl)-2,3'-anhydrothymidine 
• 1370642-72-0 C₃₇H₃₆N₂O₆Se 
• 1666-13-3 diphenyl diselenide 
• 25442-42-6 5'-O-trityl-2,3'-anhydrothymidine 
• 7481-90-5 3',4'-anhydrothymidine 
• 94892-66-7 1-(2,5-dideoxy-5-iodo-β-D-threo-pentofuranosyl)thymine 
• 142409-84-5 1-[(2R,4R,5S)-5-Iodomethyl-4-(9-phenyl-9H-xanthen-9-yloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 142409-87-8 (1R,10R,11R)-4-Methyl-11-(9-phenyl-9H-xanthen-9-yloxy)-8,13-dioxa-2,6-diaza-tricyclo[8.2.1.0^2,7]trideca-3,6-dien-5-one 
• 142409-83-4 1-[(2R,4R,5S)-5-Iodomethyl-4-(4-methoxy-tetrahydro-pyran-4-yloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 142409-85-6 Methoxy-acetic acid (1R,10R,11R)-4-methyl-5-oxo-8,13-dioxa-2,6-diaza-tricyclo[8.2.1.0^2,7]trideca-3,6-dien-11-yl ester 
• 142409-82-3 Methoxy-acetic acid (2S,3R,5R)-2-iodomethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Downstream Products

• 3056-17-5 stavudin 
• 3416-05-5 3'-Deoxythymidine 
• 1419743-18-2 3'-α-(selenophenyl)-2',3'-dideoxythymidine-5'-yl H-phosphonate triethylammonium salt 

Relevant academic research and scientific papers

Synthesis of C3′ modified nucleosides for selective generation of the C3′-deoxy-3′-thymidinyl radical: A proposed intermediate in LEE induced DNA damage

DNA damage pathways induced by low-energy electrons (LEEs) are believed to involve the formation of 2-deoxyribose radicals. These radicals, formed at the C3′ and C5′ positions of nucleotides, are the result of cleavage of the C-O phosphodiester bond throu

Action of nucleophiles on 2,3'-anhydrothymidine: Side-reactions involving the possible intermediacy of 2,5'-anhydro-1-(2-deoxy-β-D-threo-pentofuranosyl)thymine

2,3'-Anhydrothymidine (1) reacts with the sodium salt of propane-2-thiol and with sodium phenyl selenide to give 5'-substituted products [(3b) and (3c), respectively] in addition to the expected 3'-substituted 2',3'-dideoxynucleoside derivatives [(2b) and