1319716-01-2

Upstream product

• 774591-92-3 4-methoxyphenyl 2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 1319715-99-5 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl bromide 
• 1319716-00-1 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranosyl chloride 
• 19488-48-3 methyl O-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 53008-65-4 methyl 2,3,4-tri-O-benzyl-D-glucopyranoside 
• 223582-35-2 ethyl 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethylsulfonato-2-thio-α-D-gluco-hept-2-ulopyranoside 
• 223582-33-0 3,4,5,7-tetra-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-glucohept-2-ulopyranose 

Relevant academic research and scientific papers

Investigation of glycosylating properties of 1-deoxy-1-ethoxysulfonyl-hept- 2-ulopyranosyl derivatives. Synthesis of a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide

Glycosylation reactions of the ethylthio, bromo and chloro derivatives of 1-deoxy-1-ethoxysulfonyl-hept-2-ulopyranose were studied applying different acceptors under different conditions. Elimination side-reactions affording exo- and endoglycals occured in all cases, however, with different proportions. Glycosyl chloride donor was applied to glycosylate a trisaccharide acceptor obtaining a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide in high yield.