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132-20-7

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Product FOB Price Min.Order Supply Ability Supplier
Pheniramine maleate API
Cas No: 132-20-7
No Data 1 Kilogram 300 Kilogram/Month Zibo Kunran Enterprises Co. LTD Contact Supplier
Pheniramine maleate Manufacturer/High quality/Best price/In stock
Cas No: 132-20-7
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality Heniramine Maleate with high purity
Cas No: 132-20-7
No Data 1 Kilogram 30 Metric Ton/Month Simagchem Corporation Contact Supplier
PHENIRAMINE MALEATE manufacturer/supplier
Cas No: 132-20-7
No Data 1 Gram 1000 Metric Ton/Month Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd Contact Supplier
(Z)-2-butenedioate; dimethyl-[3-phenyl-3-(2-pyridin-1-iumyl)propyl]ammonium
Cas No: 132-20-7
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Supply 99% CAS 132-20-7 Pheniramine Maleate Powder
Cas No: 132-20-7
USD $ 60.0-70.0 / Gram 5 Gram 1000 Kilogram/Day Xi'an Julong Bio-Tech Co., Ltd. Contact Supplier
Pheniramine maleate
Cas No: 132-20-7
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Pheniramine maleate/132-20-7/99% purity in stock
Cas No: 132-20-7
USD $ 1.0-1.0 / Kiloliter 1 Kiloliter 10 Gram/Week Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd Contact Supplier
Pheniramine maleate CAS:132-20-7
Cas No: 132-20-7
No Data 1 Metric Ton 10 Metric Ton/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Manufacturer supply CAS 132-20-7 with best quality
Cas No: 132-20-7
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier

132-20-7 Usage

Fire Hazard

Flash point data are not available for Pheniramine maleate, but Pheniramine maleate is probably combustible.

Uses

A H1 histamine receptor antagonist.

Uses

Pheniramine, a H1-receptor antagonist, is an antihistamine with anticholinergic and sedative properties. Pheniramine is used to treat allergic conditions such as hay fever or urticaria.

Chemical Properties

white powder

Uses

Used medicinally as an antihistaminic (merck).

General Description

White powder with a faint amine-like odor. Melting point 107°C. pH (1% solution) 4.5-5.5. Used medicinally as an antihistaminic.

Reactivity Profile

Pheniramine maleate gives weakly acidic aqueous solutions. May react with strong oxidizing agents.

Uses

Antihistaminic;H1 antagonist

Air & Water Reactions

Water soluble.
InChI:InChI=1/C16H20N2.C3H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;4-2(5)1-3(6)7/h3-10,12,15H,11,13H2,1-2H3;1H2,(H,4,5)(H,6,7)

132-20-7 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (P6902)  Pheniramine maleate salt   132-20-7 P6902-5G 1,381.77CNY Detail
USP (1522301)  Pheniramine maleate  United States Pharmacopeia (USP) Reference Standard 132-20-7 1522301-150MG 4,662.45CNY Detail
Sigma-Aldrich (P0850000)  Pheniramine maleate  European Pharmacopoeia (EP) Reference Standard 132-20-7 P0850000 1,880.19CNY Detail
TCI America (P2271)  Pheniramine Maleate  >98.0%(HPLC)(T) 132-20-7 25g 690.00CNY Detail

132-20-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name Pheniramine Maleate

1.2 Other means of identification

Product number -
Other names (Z)-but-2-enedioic acid,N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132-20-7 SDS

132-20-7Synthetic route

pheniramine
86-21-5

pheniramine

maleic acid
110-16-7

maleic acid

pheniramine maleate
132-20-7

pheniramine maleate

Conditions
ConditionsYield
In ethanol at 20℃; Solvent;5.1 g
benzyl boronic acid
4463-42-7

benzyl boronic acid

pheniramine maleate
132-20-7

pheniramine maleate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide; tetrahydrofuran; water / 3 h / 75 °C / Inert atmosphere
2: potassium carbonate / N,N-dimethyl-formamide / 5 h / 80 °C
3: ethanol / 20 °C
View Scheme
2-bromo-pyridine
109-04-6

2-bromo-pyridine

pheniramine maleate
132-20-7

pheniramine maleate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide; tetrahydrofuran; water / 3 h / 75 °C / Inert atmosphere
2: potassium carbonate / N,N-dimethyl-formamide / 5 h / 80 °C
3: ethanol / 20 °C
View Scheme
potassium pentacyanonitrosylchromate(III) monohydrate

potassium pentacyanonitrosylchromate(III) monohydrate

pheniramine maleate
132-20-7

pheniramine maleate

{Cr(NO)(CN)2(pheniramine maleate)2(H2O)}

{Cr(NO)(CN)2(pheniramine maleate)2(H2O)}

Conditions
ConditionsYield
With CH3COOH In acetic acid byproducts: CH3COOK, H2O, HCN; aq. acetic acid; 20-30 min, 80°C; CO2 bubbled (few h) to remove HCN; ppt. washed (H2O repeatedly; ethanol); dried (vac., over silica gel, room temp., to const. wt.); elem.anal.;59%
tetracyanodinitrosylmolybdate(0)

tetracyanodinitrosylmolybdate(0)

pheniramine maleate
132-20-7

pheniramine maleate

Mo(NO)2(CN)2(C5H4NCH(CH2CH2N(CH3)2)C6H5)2*2(HCCOOH)2*2H2O=(Mo(NO)2(CN)2(C16H20N2)2)*((HCCOOH)2)2*2H2O

Mo(NO)2(CN)2(C5H4NCH(CH2CH2N(CH3)2)C6H5)2*2(HCCOOH)2*2H2O=(Mo(NO)2(CN)2(C16H20N2)2)*((HCCOOH)2)2*2H2O

Conditions
ConditionsYield
In water; acetic acid addn. of ligand in a mixt. of water/acetic acid to a filtered aq. soln. of molybdate with shaking, refluxing for 4-5 h over a hot plate at 80°C; filtn. by suction, washing several times with dilute acetic acid, finally with water, drying in vacuo at room temp. to a constant weight, elem. anal.;53%
pentaisothiocyanatonitrosylchromate(I)

pentaisothiocyanatonitrosylchromate(I)

pheniramine maleate
132-20-7

pheniramine maleate

Cr(NO)(NCS)2(C16H20N2)2(H2O)*2C4H4O4

Cr(NO)(NCS)2(C16H20N2)2(H2O)*2C4H4O4

Conditions
ConditionsYield
In acetic acid aq. acetic acid; shaking, reflux (80°C, 1-2 h), ice cooling, pptn.; filtration, washing (CH3COOH(aq.), water), drying (vac., room temp.); elem. anal.;45%
tetracyanonitrosylchromate(I) anion

tetracyanonitrosylchromate(I) anion

water
7732-18-5

water

pheniramine maleate
132-20-7

pheniramine maleate

[Cr(NO)(CN)2(C5H4N(C6H5)CHCH2CH2N(CH3)2)(H2O)]*HOOCCHCHCOOH

[Cr(NO)(CN)2(C5H4N(C6H5)CHCH2CH2N(CH3)2)(H2O)]*HOOCCHCHCOOH

Conditions
ConditionsYield
In water; acetic acid adding aq.-AcOH soln. of ligand to aq. soln. of Cr complex with shaking,refluxing for 30-45 min at 80°C; filtering ppt. by suction, washing with dild. AcOH and water, drying in vacuo; elem. anal.;42%

132-20-7Related news

Development and validation of a UV-spectrophotometric method for the determination of Pheniramine maleate (cas 132-20-7) and its stability studies09/30/2019

A sensitive, precise, and cost-effective UV-spectrophotometric method is described for the determination of pheniramine maleate (PAM) in bulk drug and tablets. The method is based on the measurement of absorbance of a PAM solution in 0.1 N HCl at 264 nm. As per the International Conference on Ha...detailed

Sensitive and selective spectrophotometric methods for the determination of Pheniramine maleate (cas 132-20-7) in bulk drug and in its formulations using sodium hypochlorite09/29/2019

Two simple, selective and sensitive spectrophotometric methods are described for the determination of pheniramine maleate (PAM) in pure and dosage forms. The method is based on the reaction of PAM with hypochlorite in the presence of Kolthoff buffer (phosphate-borate) of pH 7.0 to form the chlor...detailed

Assessment of Protective Effects of Methylprednisolone and Pheniramine maleate (cas 132-20-7) on Reperfusion Injury in Kidney After Distant Organ Ischemia: A Rat Model10/01/2019

Ischemia/reperfusion (I/R) injury of tissues is a common problem that cardiovascular surgeons are faced with. Suppression of inflammation, which plays an important role in the pathogenesis of I/R injury, may reduce this damage. The aim of this study is to investigate the protective effects of me...detailed

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