13209-80-8

Basic information

• Product Name: 2-Butenamide, 3-methyl-N-phenyl-
• CAS NO: 13209-80-8
• Molecular Formula: C11H13NO
• Molecular Weight: 175.23
• Mol File: 13209-80-8.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: 2-Butenamide, 3-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenamide, 3-methyl-N-phenyl-(13209-80-8)
• EPA Substance Registry System: 2-Butenamide, 3-methyl-N-phenyl-(13209-80-8)

Safety Data

• Hazardous Substances Data: 13209-80-8(Hazardous Substances Data)

Upstream product

• 99985-75-8 β-hydroxy-isovaleric acid anilide 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 62-53-3 aniline 
• 541-47-9 3-Methylbutenoic acid 
• 20411-76-1 4-ethoxy-2-methylbut-3-yn-2-ol 
• 105906-92-1 4,4-dimethyl-1-phenyl-azetidin-2-one 
• 7664-93-9 sulfuric acid 
• 75115-09-2 3-methyl-1-phenyl-2-buten-1-one (E)-oxime 
• 34876-10-3 3-methyl-2-butenoic anhydride 
• 38771-78-7 3-Bromo-3-methyl-N-phenyl-butyramide 

Downstream Products

• 76693-04-4 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one 
• 39618-55-8 3-methyl-2-methylthio-3-chlorobutanoic acid 
• 870072-60-9 4,4-dimethyl-1-(2-nitro-phenyl)-1,2,3,4-tetrahydroquinoline 
• 870072-61-0 2-(4,4-dimethyl-3,4-dihydroquinolin-1(2H)-yl)aniline 
• 13140-17-5 3-methyl-3-butenoic acid phenyl amide 
• 1070973-20-4 4-[5-chloro-4-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-(4,4-dimethyl-3,4-dihydro-2H-quinoline-1-sulfonyl)-phenoxy]-butyric acid 
• 1070973-14-6 5-[2-chloro-5-(4,4-dimethyl-3,4-dihydro-2H-quinoline-1-sulfonyl)-4-(4-hydroxy-butoxy)-phenyl]-2-trifluoromethyl-isonicotinonitrile 
• 1070973-17-9 4-[5-chloro-2-(4,4-dimethyl-3,4-dihydro-2H-quinoline-1-sulfonyl)-4-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)-phenoxy]-butan-1-ol 
• 1070973-16-8 1-[4-bromo-5-chloro-2-(4,4-dimethyl-3,4-dihydro-2H-quinoline-1-sulfonyl)-phenoxy]-butan-1-ol 
• 1070973-34-0 2-[4-bromo-5-chloro-2-(4,4-dimethyl-3,4-dihydro-2H-quinoline-1-sulfonyl)-phenyl]-malonic acid dimethyl ester 
• 1070973-35-1 2-[4-bromo-5-chloro-2-(4,4-dimethyl-3,4-dihydro-2H-quinoline-1-sulfonyl)-phenyl]-acetic acid methyl ester 
• 1070973-15-7 1-(5-bromo-4-chloro-2-fluoro-benzenesulfonyl)-4,4-dimethyl-1,2,3,4-tetrahydro-quinoline 
• 117241-97-1 4,4-dimethyl-6-nitro-3,4-dihydro-1H-quinolin-2-one 
• 873056-12-3 tert-butyl 7-amino-3,4-dihydro-4,4-dimethylquinoline-1(2H)-carboxylate 

Relevant articles and documents

4-Alkyl- and 3,4-dialkyl-1,2,3,4-tetrahydro-8-pyridono[5,6- g]quinolines: Potent, nonsteroidal androgen receptor agonists

A series of human androgen receptor (hAR) agonists based on 4-alkyl-; 4,4-dialkyl-; and 3,4-dialkyl-1,2,3,4-tetrahydro-8-pyridono[5,6-g]quinoline was synthesized and evaluated in competitive receptor binding assays and an androgen receptor cotransfection assay in a mammalian cell background. A number of compounds in this series demonstrated activity equal to or better than dihydrotestosterone in both assays and represent a novel class of compounds for use in androgen replacement therapy.

Enantioselective syn-selective scandium-catalyzed ene reactions

An enantio- and diastereoselective carbonyl-ene reaction catalyzed by chiral scandium pyridyl bis(oxazoline) (pybox) complexes has been developed. Uniformly high enantiomeric excesses and good yields were observed. Use of trisubstituted olefins generated

Synthesis, Reactivity, Functionalization, and ADMET Properties of Silicon-Containing Nitrogen Heterocycles

Silicon-containing compounds have been largely ignored in drug design and development, despite their potential to improve not only the potency but also the physicochemical and ADMET (absorption, distribution, metabolism, excretion, toxicity) properties of drug-like candidates because of the unique characteristics of silicon. This deficiency is in large part attributable to a lack of general methods for synthesizing diverse organosilicon structures. Accordingly, a new building block strategy has been developed that diverges from traditional approaches to incorporation of silicon into drug candidates. Flexible, multi-gram-scale syntheses of silicon-containing tetrahydroquinoline and tetrahydroisoquinoline building blocks are described, along with methods by which diversely functionalized silicon-containing nitrogen heterocycles can be rapidly built using common reactions optimized to accommodate the properties of silicon. Furthermore, to better clarify the liabilities and advantages of silicon incorporation, select compounds and their carbon analogues were challenged in ADMET-focused biological studies.

USE OF SUBSTITUTE OXO TETRAHYDROQUINOLINE SULFONAMIDES OR SALTS THEREOF FOR RAISING STRESS TOLERANCE OF PLANTS

The invention relates to the use of substituted oxotetrahydroquinolinylsulfonamides or salts thereof where the radicals in the general formula (I) correspond to the definitions given in the description, for enhancing stress tolerance in plants to abiotic stress, and/or for increasing plant yield.